Recombinant Human SRC protein, His-tagged
Cat.No. : | SRC-3525H |
Product Overview : | Recombinant Human SRC protein(P12931)(2-536aa), fused to N-terminal His tag, was expressed in E. coli. |
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Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Molecular Mass : | 64.2 kDa |
Protein length : | 2-536aa |
AA Sequence : | GSNKSKPKDASQRRRSLEPAENVHG AGGGAFPASQTPSKPASADGHRGPS AAFAPAAAEPKLFGGFNSSDTVTSP QRAGPLAGGVTTFVALYDYESRTET DLSFKKGERLQIVNNTEGDWWLAHS LSTGQTGYIPSNYVAPSDSIQAEEW YFGKITRRESERLLLNAENPRGTFL VRESETTKGAYCLSVSDFDNAKGLN VKHYKIRKLDSGGFYITSRTQFNSL QQLVAYYSKHADGLCHRLTTVCPTS KPQTQGLAKDAWEIPRESLRLEVKL GQGCFGEVWMGTWNGTTRVAIKTLK PGTMSPEAFLQEAQVMKKLRHEKLV QLYAVVSEEPIYIVTEYMSKGSLLD FLKGETGKYLRLPQLVDMAAQIASG MAYVERMNYVHRDLRAANILVGENL VCKVADFGLARLIEDNEYTARQGAK FPIKWTAPEAALYGRFTIKSDVWSF GILLTELTTKGRVPYPGMVNREVLD QVERGYRMPCPPECPESLHDLMCQC WRKEPEERPTFEYLQAFLEDYFTST EPQYQPGENL |
Purity : | Greater than 85% as determined by SDS-PAGE. |
Storage : | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Reconstitution : | Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. |
Gene Name : | SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) [ Homo sapiens ] |
Official Symbol : | SRC |
Synonyms : | SRC; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); SRC1, v src avian sarcoma (Schmidt Ruppin A 2) viral oncogene homolog; proto-oncogene tyrosine-protein kinase Src; ASV; c src; proto-oncogene c-Src; tyrosine kinase pp60c-src; tyrosine-protein kinase SRC-1; protooncogene SRC, Rous sarcoma; SRC1; c-SRC; p60-Src; |
Gene ID : | 6714 |
mRNA Refseq : | NM_005417 |
Protein Refseq : | NP_005408 |
MIM : | 190090 |
UniProt ID : | P12931 |
Products Types
◆ Native Protein | ||
SRC-29697TH | Native Human SRC | +Inquiry |
◆ Lysates | ||
SRC-585MCL | Recombinant Mouse SRC cell lysate | +Inquiry |
SRC-487HCL | Recombinant Human SRC cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionChanges in SRC expression or kinase activity can lead to drug resistance in cancer treatment.
SRC regulates cell proliferation and survival through its kinase activity, influencing various signaling pathways.
SRC is involved in bone remodeling, regulating osteoclast activity and bone resorption.
SRC plays a crucial role in cancer progression, particularly in enhancing metastatic potential of tumor cells.
SRC influences key cellular signaling pathways like Ras/MAPK and PI3K/Akt, affecting cell growth and survival.
SRC modulates cellular adhesion and migration, playing a role in tissue repair and cancer metastasis.
SRC inhibition is a target in cancer therapy, potentially reducing tumor growth and metastasis.
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