Active Recombinant Mouse Chemokine (C-X-C motif) Ligand 1
Cat.No. : | Cxcl1-384M |
Product Overview : | Recombinantmouse Cxcl1 protein was expressed in E. coli. Arg20-Lys96. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Cxcl1-384M |
Description : | Cxcl1 is a smallcytokine belonging to the CXC chemokine family that was previously calledGRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3) and melanomagrowth stimulating activity, alpha (MSGA-α). |
Source : | E. coli |
Form : | Lyophilized from a0.2 μm filtered solution in PBS with BSA as a carrier protein. |
N-terminal Sequence : | Arg29 |
Molecular Weight : | 8 kDa |
Activity : | Measured by itsability to induce myeloperoxidase release from cytochalasin B-treated humanneutrophils. The ED50 for this effect is typically 0.3-0.9 μg/mL.Measured by its ability to chemoattract human CXCR2 transfected BaF3 mousepro-B cells. The ED50 for this effect is typically 3-15 ng/mL. |
Endotoxin Level : | <1.0 EU per 1 μgof the protein by the LAL method. |
Purity : | >97%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | Reconstitute at 100μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin. |
Storage : | Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1month, -20 to -70°C under sterile conditions after reconstitution. 3 months, -70°Cunder sterile conditions after reconstitution. |
Gene Name : | Cxcl1chemokine (C-X-C motif) ligand 1 [ Mus musculus ] |
Official Symbol : | Cxcl1 |
Synonyms : | Cxcl1; chemokine(C-X-C motif) ligand 1; KC; Fsp; N51; gro; Gro1; Mgsa; Scyb1; OTTMUSP00000018305;growth-regulatedalpha protein; KC/GRO-alpha; (KC/GR)-alpha; GRO1 oncogene; secretory proteinN51; C-X-C motif chemokine 1; platelet-derived growth factor-inducibleprotein KC; Hematopoietic synergistic factor;HSF; KC-T |
Gene ID : | 14825 |
mRNA Refseq : | NM_008173 |
Protein Refseq : | NP_032202 |
UniProt ID : | P12850 |
Chromosome Location : | 5 |
Pathway : | Chemokine receptorsbind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-likereceptors); Cytokine-cytokine receptor interaction; Cytokines andInflammatory Response (BioCarta); G alpha (i) signalling events; GPCRdownstream signaling; GPCR ligand binding; Legionellosis; NOD-like receptorsignaling pathway; Peptide ligand-binding receptors; Salmonella infection;Signal Transduction; Signaling by GPCR |
Function : | chemokine activity;cytokine activity; growth factor activity |
Products Types
◆ Recombinant Protein | ||
CXCL1-272C | Active Recombinant Human CXCL1 Protein | +Inquiry |
CXCL1-178C | Recombinant Cynomolgus Monkey CXCL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cxcl1-33M | Active Recombinant Mouse Cxcl1 Protein (Asn29-Lys96), Animal-free, Carrier-free | +Inquiry |
CXCL1-982H | Recombinant Human CXCL1 Protein, His-SUMO-tagged | +Inquiry |
CXCL1-929R | Recombinant Rhesus Macaque CXCL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
CXCL1-27707TH | Native Human CXCL1 | +Inquiry |
◆ Lysates | ||
CXCL1-425HCL | Recombinant Human CXCL1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionTherapeutic strategies targeting CXCL1 aim to modulate its activity in diseases like cancer and chronic inflammation.
It mediates inflammation by promoting leukocyte migration and activation.
In cancer, CXCL1 can promote tumor growth, metastasis, and angiogenesis.
CXCL1 contributes to angiogenesis, supporting new blood vessel formation.
CXCL1 is a chemokine that attracts neutrophils to sites of infection or injury.
CXCL1 levels are elevated in conditions like cancer, inflammatory diseases, and infections.
CXCL1 expression is regulated by various stimuli, including cytokines and growth factors.
Customer Reviews (3)
Write a reviewEfficient delivery, great service.
Product as described, perfect.
Reliable for protein work.
Ask a Question for All Cxcl1 Products
Required fields are marked with *
My Review for All Cxcl1 Products
Required fields are marked with *
Inquiry Basket