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Active Recombinant Mouse Chemokine (C-X-C motif) Ligand 1
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Cat.No. : | Cxcl1-384M Optional Service: Optional requirements on this protein |
Product Overview : | Recombinantmouse Cxcl1 protein was expressed in E. coli. Arg20-Lys96. |
Description : | Cxcl1 is a smallcytokine belonging to the CXC chemokine family that was previously calledGRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3) and melanomagrowth stimulating activity, alpha (MSGA-α). |
Source : | E. coli |
Form : | Lyophilized from a0.2 μm filtered solution in PBS with BSA as a carrier protein. |
N-terminal Sequence : | Arg29 |
Molecular Weight : | 8 kDa |
Activity : | Measured by itsability to induce myeloperoxidase release from cytochalasin B-treated humanneutrophils. The ED50 for this effect is typically 0.3-0.9 μg/mL.Measured by its ability to chemoattract human CXCR2 transfected BaF3 mousepro-B cells. The ED50 for this effect is typically 3-15 ng/mL. |
Endotoxin Level : | <1.0 EU per 1 μgof the protein by the LAL method. |
Purity : | >97%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | Reconstitute at 100μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin. |
Storage : | Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1month, -20 to -70°C under sterile conditions after reconstitution. 3 months, -70°Cunder sterile conditions after reconstitution. |
PDB rendering based on 1mgs. : |
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Gene Name : | Cxcl1chemokine (C-X-C motif) ligand 1 [ Mus musculus ] |
Official Symbol : | Cxcl1 |
Synonyms : | Cxcl1; chemokine(C-X-C motif) ligand 1; KC; Fsp; N51; gro; Gro1; Mgsa; Scyb1; OTTMUSP00000018305;growth-regulatedalpha protein; KC/GRO-alpha; (KC/GR)-alpha; GRO1 oncogene; secretory proteinN51; C-X-C motif chemokine 1; platelet-derived growth factor-inducibleprotein KC; Hematopoietic synergistic factor;HSF; KC-T |
Gene ID : | 14825 |
mRNA Refseq : | NM_008173 |
Protein Refseq : | NP_032202 |
UniProt ID : | P12850 |
Chromosome Location : | 5 |
Pathway : | Chemokine receptorsbind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-likereceptors); Cytokine-cytokine receptor interaction; Cytokines andInflammatory Response (BioCarta); G alpha (i) signalling events; GPCRdownstream signaling; GPCR ligand binding; Legionellosis; NOD-like receptorsignaling pathway; Peptide ligand-binding receptors; Salmonella infection;Signal Transduction; Signaling by GPCR |
Function : | chemokine activity;cytokine activity; growth factor activity |
◆ Recombinant Protein
CXCL1-001H | Recombinant Human CXCL1 Protein, MBP-tagged | +Inquiry |
Cxcl1-068M | Recombinant Mouse Cxcl1 Protein | +Inquiry |
CXCL1-2155H | Recombinant Human CXCL1 Protein, GST-tagged | +Inquiry |
CXCL1-53H | Recombinant Human CXCL1 Protein | +Inquiry |
Cxcl1-53M | Recombinant Mouse CXCL1 Protein | +Inquiry |
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◆ Native Protein
CXCL1-27707TH | Native Human CXCL1 | +Inquiry |
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◆ Lysates
CXCL1-425HCL | Recombinant Human CXCL1 cell lysate | +Inquiry |
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CXCL1Cxcl10CXCL11CXCL12CXCL13CXCL14Cxcl15Cxcl16Cxcl2CXCL3Cxcl5CXCL6CXCL9Cxcl17CXCL7
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