Active Recombinant Mouse Chemokine (C-X-C motif) Ligand 1 Cxcl1-384M

Active Recombinant Mouse Chemokine (C-X-C motif) Ligand 1

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Cat.No. : Cxcl1-384M Optional Service: Optional requirements on this protein
Product Overview : Recombinantmouse Cxcl1 protein was expressed in E. coli. Arg20-Lys96.
Description : Cxcl1 is a smallcytokine belonging to the CXC chemokine family that was previously calledGRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3) and melanomagrowth stimulating activity, alpha (MSGA-α).
Source : E. coli
Form : Lyophilized from a0.2 μm filtered solution in PBS with BSA as a carrier protein.
N-terminal Sequence : Arg29
Molecular Weight : 8 kDa
Activity : Measured by itsability to induce myeloperoxidase release from cytochalasin B-treated humanneutrophils. The ED50 for this effect is typically 0.3-0.9 μg/mL.Measured by its ability to chemoattract human CXCR2 transfected BaF3 mousepro-B cells. The ED50 for this effect is typically 3-15 ng/mL.
Endotoxin Level : <1.0 EU per 1 μgof the protein by the LAL method.
Purity : >97%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 100μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin.
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1month, -20 to -70°C under sterile conditions after reconstitution. 3 months, -70°Cunder sterile conditions after reconstitution.
PDB rendering based on 1mgs. :

Gene Name : Cxcl1chemokine (C-X-C motif) ligand 1 [ Mus musculus ]
Official Symbol : Cxcl1
Synonyms : Cxcl1; chemokine(C-X-C motif) ligand 1; KC; Fsp; N51; gro; Gro1; Mgsa; Scyb1; OTTMUSP00000018305;growth-regulatedalpha protein; KC/GRO-alpha; (KC/GR)-alpha; GRO1 oncogene; secretory proteinN51; C-X-C motif chemokine 1; platelet-derived growth factor-inducibleprotein KC; Hematopoietic synergistic factor;HSF; KC-T
Gene ID : 14825
mRNA Refseq : NM_008173
Protein Refseq : NP_032202
UniProt ID : P12850
Chromosome Location : 5
Pathway : Chemokine receptorsbind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-likereceptors); Cytokine-cytokine receptor interaction; Cytokines andInflammatory Response (BioCarta); G alpha (i) signalling events; GPCRdownstream signaling; GPCR ligand binding; Legionellosis; NOD-like receptorsignaling pathway; Peptide ligand-binding receptors; Salmonella infection;Signal Transduction; Signaling by GPCR
Function : chemokine activity;cytokine activity; growth factor activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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