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Recombinant Human CCL20
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Cat.No. : | CCL20-296H |
Product Overview : | Recombinant human MIP-3α is a non-glycosylated protein, containing 70 amino acids and a molecular weight of 8.0 kDa. |
Description : | Macrophage Inflammatory Protein-3 alpha (MIP-3α), also called CCL20, is expressed in the liver, lungs, lymph nodes and peripheral blood lymphocytes. MIP-3α is strongly up regulated by inflammatory signals, and down regulated by the antiinflammatory cytokine IL-10. MIP-3α signals through the G protein-coupled receptor, CCR6, and acts as a chemoattractant to lymphocytes and dendritic cells. |
Source : | E.coli |
Species : | Human |
Appearance : | Sterile filtered white lyophilized (freeze-dried) powder. |
Form : | Recombinant human MIP-3α is lyophilized with no additives. |
Bio-activity : | The activity is determined by its ability to act as a chemoattractant to human T cells and is typically in the range of 7 - 70 ng/mL. |
Molecular Mass : | 8.0 kDa |
AA Sequence : | ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM |
Endotoxin : | Measured by kinetic LAL analysis and is typically ≤ 1 EU/μg protein. |
Purity : | ≥ 97% |
Stability : | Lyophilized product is very stable at -20°C. Reconstituted material should be aliquoted and frozen at -20°C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage. |
Reconstitution : | Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/mL, which can be further diluted into other aqueous solutions. |
Gene Name : | CCL20 chemokine (C-C motif) ligand 20 [ Homo sapiens (human) ] |
Official Symbol : | CCL20 |
Synonyms : | CCL20; CKb4; LARC; ST38; MIP3A; MIP-3a; SCYA20; MIP-3-alpha; C-C motif chemokine 20; chemokine (C-C motif) ligand 20; CC chemokine LARC; beta chemokine exodus-1; small-inducible cytokine A20; macrophage inflammatory protein 3 alpha; liver and activation-regulated chemokine; small inducible cytokine subfamily A (Cys-Cys), member 20 |
Gene ID : | 6364 |
mRNA Refseq : | NM_004591 |
Protein Refseq : | NP_004582 |
MIM : | 601960 |
UniProt ID : | P78556 |
Chromosome Location : | 2q36.3 |
Pathway : | Chemokine receptors bind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-like receptors) |
Function : | chemokine activity |
◆ Recombinant Protein
CCL20-793M | Recombinant Mouse CCL20 Protein (Ala28-Met97) | +Inquiry |
CCL20-1082B | Recombinant Bovine CCL20 Protein (27-96 aa), His-SUMO-tagged | +Inquiry |
Ccl20-2888R | Recombinant Rat Ccl20 Protein | +Inquiry |
CCL20-516H | Recombinant Human CCL20 Protein, MIgG2a Fc-tagged | +Inquiry |
CCL20-4364R | Recombinant Rabbit CCL20 Protein | +Inquiry |
|
◆ Lysates
CCL20-447MCL | Recombinant Mouse CCL20 cell lysate | +Inquiry |
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CCL1 CCL11 Ccl12 CCL13 CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL2 CCL20 CCL21 Ccl21c CCL22 CCL23 CCL24 CCL25 CCL26 CCL27 Ccl27a CCL28 CCL3 CCL3L1 Ccl4 CCL5 Ccl6 CCL7 CCL8 Ccl9 CCL4L2 Ccl21a CCL4L1 CCL3L3 Ccl21b Ccl27b
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