• Official Full Name

    chemokine (C-C motif) ligand 20

  • Background

    Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family. It is strongly chemotactic for lymphocytes and weakly attracts neutrophils. CCL20 is implicated in the formation and function of mucosal lymphoid tissues via chemoattraction of lymphocytes and dendritic cells towards the epithelial cells surrounding these tissues. CCL20 elicits its effects on its target cells by binding and activating the chemokine receptor CCR6.
  • Synonyms

    CCL20; chemokine (C-C motif) ligand 20; CKb4; LARC; ST38; MIP3A; MIP-3a; SCYA20; C-C motif chemokine 20; exodus-1; MIP-3-alpha; CC chemokine LARC; OTTHUMP00000164245; OTTHUMP00000204113; beta chemokine exodus-1; beta-chemokine exodus-1; small-inducible cytokine A20; macrophage inflammatory protein 3 alpha; liver and activation-regulated chemokine; small inducible cytokine subfamily A (Cys-Cys), member 20; MIP-3[a]; OTTMUSP00000017965; OTTMUSP00000017966;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Bovine
    • Chicken
    • Human
    • Macaca mulatta
    • Mouse
    • Rabbit
    • Rat
    • Rhesus macaque
    • Rhesus Macaque
    • Source :
    • CHO
    • E. coli
    • E.coli
    • HEK293
    • Human Cells
    • In Vitro Cell Free System
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • Biotin
    • Fc
    • GST
    • HIgG1 Fc
    • His
    • His (Fc)
    • Avi
    • His|GST
    • His|SUMO
    • MIgG2a Fc
    • N/A
    • N
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Bovine CCL20-1082B Recombinant Bovine CCL20 Protein (27-96 aa), His-SUMO-tagged E.coli His/SUMO
    Bovine CCL20-5807B Recombinant Bovine CCL20 protein, His-tagged Yeast His
    Chicken CCL20-6008C Recombinant Chicken CCL20 Mammalian Cell His
    Chicken CCL20-136C Recombinant Chicken Chemokine (C-C motif) Ligand 20 Yeast N/A
    Human CCL20-166H Recombinant Human CCL20, His-tagged E.coli His
    Human CCL20-517H Recombinant Human CCL20 Protein, HIgG1 Fc-tagged CHO HIgG1 Fc
    Human CCL20-296H Active Recombinant Human CCL20 E.coli N/A
    Human CCL20-11H Recombinant Human CCL20 protein E.coli N/A
    Human CCL20-61H Recombinant Human CCL20 Protein, Biotin-tagged E.coli Biotin
    Human CCL20-22H Recombinant Human CCL20 Protein CHO N/A
    Human CCL20-161H Recombinant Human CCL20, His tagged E.coli His
    Human CCL20-515H Recombinant Human CCL20 Protein, HIgG1 Fc-tagged, mutant CHO HIgG1 Fc
    Human CCL20-0624H Recombinant Human CCL20 Protein, GST-Tagged Wheat Germ GST
    Human CCL20-518H Recombinant Human CCL20 Protein, Fc-tagged HEK293 Fc
    Human CCL20-717H Recombinant Human CCL20 protein, His & GST-tagged E.coli His/GST
    Human CCL20-516H Recombinant Human CCL20 Protein, MIgG2a Fc-tagged CHO MIgG2a Fc
    Human CCL20-2651H Recombinant Human CCL20 protein, GST-tagged E.coli GST
    Human CCL20-641H Recombinant Human CCL20 Protein, GST-tagged E.coli N-GST
    Human CCL20-327C Recombinant Human CCL20 Protein (70 aa) E.coli
    Human CCL20-47H Recombinant Human CCL20 Protein E.coli
    Human CCL20-2951HF Recombinant Full Length Human CCL20 Protein, GST-tagged In Vitro Cell Free System GST
    Human CCL20-218C Recombinant Human CCL20 Protein (70 aa) CHO
    Human CCL20-17H Recombinant Human CCL20 Protein E.coli
    Human CCL20-151H Recombinant Human CCL20 Protein, His-tagged Human Cells His
    Human CCL20-073C Recombinant Human CCL20 Protein (70 aa) E.coli
    Human CCL20-0752H Recombinant Human CCL20 Protein (Ser28-Met96), N-His tagged E.coli N-His
    Macaca mulatta CCL20-15M Recombinant Macaca mulatta CCL20 protein, GST-tagged E.coli GST
    Mouse Ccl20-833M Recombinant Mouse Ccl20 Protein, His-tagged Insect Cell His
    Mouse Ccl20-2032M Recombinant Mouse Ccl20 Protein E. coli
    Mouse CCL20-793M Recombinant Mouse CCL20 Protein (Ala28-Met97) E.coli N/A
    Mouse CCL20-50M Recombinant Mouse CCL20 protein E.coli N/A
    Mouse CCL20-447MCL Recombinant Mouse CCL20 cell lysate Insect Cell N/A
    Mouse CCL20-18M Recombinant Mouse CCL20 Protein E.coli
    Rabbit CCL20-4364R Recombinant Rabbit CCL20 Protein Yeast N/A
    Rat Ccl20-2888R Recombinant Rat Ccl20 Protein E.coli N/A
    Rat Ccl20-719R Recombinant Rat Ccl20 protein, His & GST-tagged E.coli His/GST
    Rat CCL20-870R-B Recombinant Rat CCL20 Protein Pre-coupled Magnetic Beads HEK293
    Rat Ccl20-409R Active Recombinant Rat Chemokine (C-C motif) Ligand 20 E.coli N/A
    Rat Ccl20-170C Recombinant Rat Ccl20 Protein (71 aa) HEK293
    Rat CCL20-1212R Recombinant Rat CCL20 Protein Mammalian Cell His
    Rat CCL20-870R Recombinant Rat CCL20 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus Macaque CCL20-684R Recombinant Rhesus monkey CCL20 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque CCL20-512R-B Recombinant Rhesus Macaque CCL20 Protein Pre-coupled Magnetic Beads HEK293
    Rhesus macaque CCL20-2652R Recombinant Rhesus macaque CCL20 protein, His-GST-tagged E.coli His/GST
    Rhesus Macaque CCL20-512R Recombinant Rhesus Macaque CCL20 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • CCL20 Related Articles
    • CCL20 Related Gene Family
    • CCL20 Related Research Area

    CCL20 involved in several pathways and played different roles in them. We selected most pathways CCL20 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, TNF signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interactionTNFRSF13C;VEGFAB;TNFRSF10B;IFNW1;CCL27B;TGFB1;TNFSF14;IL2RG;LEPB
    Chemokine signaling pathwayHCK;CCR10;CCL6;PLCB1;VAV2;MAPK3;LYN;GRK7;PAK1
    TNF signaling pathwayRPS6KA5;PGAM5;NFKB1;AKT2;ATF4;BCL3;MAP3K5;IKBKB;VEGFC
    Rheumatoid arthritisIL17A;ATP6V0D2;TNFRSF11A;CCL2;GM-CSF;TGFB3;VEGFA;CCL3;ATP6V0E1

    CCL20 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL20 itself. We selected most functions CCL20 had, and list some proteins which have the same functions with CCL20. You can find most of the proteins on our site.

    Function Related Protein
    CCR chemokine receptor bindingCCL34B.1;CCL20B;CCL44;CCL19;CCL34B.4;CCL22;CX3CL1;CCL15;CCL38A.5
    chemokine activityCCL2;AMCF-II;CCL38A.4;CCL21B;IL-8;CXCL2;CCL3;CCL5;CCL14
    protein bindingC16orf87;TRAPPC10;KRT1;KLRG1;PLD1;RTN4;NFIL3;DDB2;ACMSD

    CCL20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL20 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL20.


    Qin, T; Yin, YY; et al. Whole inactivated avian Influenza H9N2 viruses induce nasal submucosal dendritic cells to sample luminal viruses via transepithelial dendrites and trigger subsequent DC maturation. VACCINE 33:1382-1392(2015).
    Wu, HH; Hwang-Verslues, WW; et al. Targeting IL-17B-IL-17RB signaling with an anti-IL-17RB antibody blocks pancreatic cancer metastasis by silencing multiple chemokines. JOURNAL OF EXPERIMENTAL MEDICINE 212:333-349(2015).
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