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Active Recombinant Rat Chemokine (C-C motif) Ligand 20
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Cat.No. : | Ccl20-409R Optional Service: Optional requirements on this protein |
Product Overview : | Recombinantrat Ccl20 protein was expressed in E. coli. Ala26-Met96. |
Description : | Ccl20, also known asMIP3α, LARC (Liver and Activationregulated Chemokine) and as Exodus, is oneof many novel β chemokines identified through bioinformatics. Rat Ccl20 cDNAencodes a 96 amino acid (aa) precursor protein with a 25 aa putative signalpeptide that is predicted to be cleaved to form the 71 aa mature secretedprotein. |
Source : | E. coli |
Form : | Lyophilized from a0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrierprotein. |
N-terminal Sequence : | Ala26 |
Molecular Weight : | 8.2 kDa |
Activity : | Measured by itsability to chemoattract human CCR6 transfected BaF3 mouse pro-B cells. The ED50for this effect is typically 0.5-3 μg/mL. |
Endotoxin Level : | <1.0 EU per 1 μgof the protein by the LAL method. |
Purity : | >97%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | Reconstitute at 200μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin. |
Storage : | Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month,2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions afterreconstitution. |
PDBrendering based on 1m8a. : |
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Gene Name : | Ccl20 chemokine (C-C motif)ligand 20 [ Rattus norvegicus ] |
Official Symbol : | Ccl20 |
Synonyms : | Ccl20; chemokine(C-C motif) ligand 20; ST38; Scya20; MIP-3-alpha; CCchemokine LARC; CC chemokine ST38; beta chemokine exodus-1; small-induciblecytokine A20; macrophage inflammatory protein 3 alpha; liver andactivation-regulated chemokine; beta-chemokine exodus-1; small induciblecytokine subfamily A20; C-C motif chemokine 20 |
Gene ID : | 29538 |
mRNA Refseq : | NM_019233 |
Protein Refseq : | NP_062106 |
UniProt ID : | P97884 |
Chromosome Location : | 9q34 |
Pathway : | Chemokine receptors bind chemokines; Chemokinesignaling pathway; Class A/1 (Rhodopsin-like receptors); Cytokine-cytokinereceptor interaction; G alpha (i) signalling events; GPCR downstreamsignaling; GPCR ligand binding; Peptide ligand-binding receptors; Rheumatoidarthritis; Signal Transduction; Signaling by GPCR |
Function : | chemokine activity; cytokine activity |
◆ Recombinant Protein
Ccl20-2032M | Recombinant Mouse Ccl20 Protein | +Inquiry |
CCL20-641H | Recombinant Human CCL20 Protein, GST-tagged | +Inquiry |
CCL20-515H | Recombinant Human CCL20 Protein, HIgG1 Fc-tagged, mutant | +Inquiry |
CCL20-218C | Recombinant Human CCL20 Protein (70 aa) | +Inquiry |
CCL20-18M | Recombinant Mouse CCL20 Protein | +Inquiry |
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◆ Lysates
CCL20-447MCL | Recombinant Mouse CCL20 cell lysate | +Inquiry |
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CCL1CCL11Ccl12CCL13CCL14CCL15CCL16CCL17CCL18CCL19CCL2CCL20CCL21Ccl21cCCL22CCL23CCL24CCL25CCL26CCL27Ccl27aCCL28CCL3CCL3L1Ccl4CCL5Ccl6CCL7CCL8Ccl9CCL4L2Ccl21aCCL4L1CCL3L3Ccl21bCcl27b
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