Recombinant Human IL12A, His-tagged
Cat.No. : | IL12A-42H |
Product Overview : | Recombinant Human Interleukin-10 produced inE.Coliis single, a non-glycosylated, Polypeptide chain containing 160 amino acids fragment (19-178) and having a total molecular mass of 18.6 kDa with an amino-terminal His-tagged. The IL-10 His-Tag is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
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Cat. No. : | IL12A-42H |
Description : | Interleukin-10 is a multifunctional cytokine produced by a variety of cell types including T helper cells activated B cells and activated macrophages. Interleukin-10 regulates immune-mediated inflammation and modulates the function of cells such as lymphocytes, monocytes, natural killer cells and dendritic cells. |
Source : | Escherichia Coli. |
Physical Appearance : | Sterile Filtered clear solution (0.083mg/1ml) |
Purity : | Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
Formulation : | Interleukin-12 p35 His-Tag is supplied in 20mM Tris HCL pH=8, 0.5 mM DTT and 50% glycerol. |
Storage : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
Gene Name : | IL12A interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) [ Homo sapiens ] |
Synonyms : | NKSF1; CTL maturation factor (TCMF); Cytotoxic lymphocyte maturation factor 35 kDa subunit (CLMF p35); TSF; Edodekin-alpha; IL-12 p35; SGT2; FLJ39002; CLMF; IL-12A; NFSK; P35; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12 subunit p35; IL-12, subunit p35; NF cell stimulatory factor chain 1; cytotoxic lymphocyte maturation factor 1, p35; interleukin 12, p35; interleukin 12A; interleukin 12A (natural killer cell stimulatory factor 1,cytotoxic lymphocytematuration factor 1, p35); interleukin-12 alpha chain; natural killer cell stimulatory factor 1, 35 kD subunit 2; IL12A. |
Gene ID : | 3592 |
mRNA Refseq : | NM_000882 |
Protein Refseq : | NP_000873 |
MIM : | 161560 |
UniProt ID : | P29459 |
Chromosome Location : | 3q25.33-q26 |
Pathway : | Allograft rejection; Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway; Type I diabetes mellitus |
Function : | contributes_to cytokine activity; contributes_to growth factor activity; interleukin-12 beta subunit binding; interleukin-12 receptor binding; interleukin-27 binding; protein binding; protein heterodimerization activity |
Products Types
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IL12A-2050R | Recombinant Rhesus Macaque IL12A Protein, His (Fc)-Avi-tagged | +Inquiry |
Il12a-140M | Recombinant Active Mouse IL12A Protein, His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
IL12A-001CCL | Recombinant Cynomolgus IL12A cell lysate | +Inquiry |
IL12A-2435HCL | Recombinant Human IL12A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionMass spectrometry identifies IL12A's post-translational modifications and their roles.
Knockout models validate IL12A's roles in immune response modulation.
Protein footprinting assays reveal IL12A's binding interfaces with receptors.
ELISA and stability assays quantify IL12A secretion and stability in culture.
SPR characterizes IL12A's interactions with antibodies and inhibitors.
Cellular assays gauge IL12A's cytokine induction in immune cells.
Isothermal titration calorimetry measures IL12A's binding affinity with receptors.
Structural biology techniques analyze IL12A genetic variant impacts.
Site-directed mutagenesis probes IL12A's functional domains and interactions.
Bioluminescence imaging tracks IL12A expression dynamics in vivo.
Customer Reviews (3)
Write a reviewSuitable for co-immunoprecipitation.
Consistent in bioactivity.
Good for receptor binding studies.
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