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Recombinant Human S100A1

Cat.No.: S100A1-31005TH
Product Overview: Recombinant full-length Human S100 alpha. Predicted Mw: 11kDa.
Description: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
Source: E. coli
Tissue specificity: Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain.
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 50mM Sodium chloride, 20mM HEPES, 1mM DTT, 1mM EDTA, pH 7
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the S-100 family.Contains 2 EF-hand domains.
Gene Name: S100A1 S100 calcium binding protein A1 [ Homo sapiens ]
Official Symbol: S100A1
Synonyms: S100A1; S100 calcium binding protein A1; S100 calcium binding protein A1 , S100A; protein S100-A1; S100 alpha;
Gene ID: 6271
mRNA Refseq: NM_006271
Protein Refseq: NP_006262
MIM: 176940
Uniprot ID: P23297
Chromosome Location: 1q21
Function: ATPase binding; S100 alpha binding; S100 beta binding; calcium ion binding; identical protein binding;

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