||Recombinant full-length Human S100 alpha. Predicted Mw: 11kDa.
||The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
||Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain.
||>95% by SDS-PAGE
||Preservative: NoneConstituents: 50mM Sodium chloride, 20mM HEPES, 1mM DTT, 1mM EDTA, pH 7
||Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
||Belongs to the S-100 family.Contains 2 EF-hand domains.