| Description : |
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014] |
| Source : |
E. coli |
| Species : |
Human |
| Tag : |
His(N-ter) |
| Form : |
Powder |
| Bio-activity : |
Measured by its ability to agglutinate human red blood cells. The ED50 for this effect is < 8 μg/mL. |
| AA Sequence : |
ADNFSLHDALSGSGNPNPQGWPGAW GNQPAGAGGYPGASYPGAYPGQAPP GAYPGQAPPGAYPGAPGAYPGAPAP GVYPGPPSGPGAYPSSGQPSATGAY PATGPYGAPAGPLIVPYNLPLPGGV VPRMLITILGTVKPNANRIALDFQR GNDVAFHFNPRFNENNRRVIVCNTK LDNNWGREERQSVFPFESGKPFKIQ VLVEPDHFKVAVNDAHLLQYNHRVK KLNEISKLGISGDIDLTSASYTMI |
| Endotoxin : |
Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. |
| Purity : |
> 95% (by SDS-PAGE) |
| Applications : |
SDS-PAGE |
| Notes : |
For laboratory research only, not for drug, diagnostic or other use. |
| Storage : |
Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Storage Buffer : |
PBS (pH 7.4) |
| Reconstitution : |
It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
