Recombinant Active Mouse IL13 Protein, His-tagged(C-ter)
| Cat.No. : | Il13-144M |
| Product Overview : | Recombinant Active Mouse IL13 Protein with His tag (C-ter) was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
| Description : | This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008] |
| Source : | E. coli |
| Species : | Mouse |
| Tag : | His(C-ter) |
| Form : | Powder |
| Bio-activity : | Determined by its ability to induce TF-1 cells proliferation. The ED50 for this effect is < 4 ng/mL. The specific activity of recombinant mouse IL-13 is > 2.5 x 10^5 IU/mg. |
| AA Sequence : | MPVPRSVSLPLTLKELIEELSNITQ DQTPLCNGSMVWSVDLAAGGFCVAL DSLTNISNCNAIYRTQRILHGLCNR KAPTTVSSLPDTKIEVAHFITKLLS YTKQLFRHGPF |
| Endotoxin : | Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. |
| Purity : | > 95% (by SDS-PAGE) |
| Applications : | SDS-PAGE |
| Notes : | For laboratory research only, not for drug, diagnostic or other use. |
| Storage : | Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Storage Buffer : | PBS (pH 7.4) |
| Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Gene Name : | Il13 interleukin 13 [ Mus musculus ] |
| Official Symbol : | Il13 |
| Synonyms : | IL13; interleukin 13; interleukin-13; T-cell activation protein P600; Il-13; |
| Gene ID : | 16163 |
| mRNA Refseq : | NM_008355 |
| Protein Refseq : | NP_032381 |
Products Types
| ◆ Recombinant Protein | ||
| IL13-504H | Recombinant Human IL13 Protein, Fc-tagged | +Inquiry |
| Il13-090M | Active Recombinant Mouse Il13 Protein | +Inquiry |
| Il13-089M | Recombinant Mouse Il13 Protein | +Inquiry |
| IL13-255I | Active Recombinant Human IL13 Protein | +Inquiry |
| IL13-132H | Active Recombinant Human IL13 Protein | +Inquiry |
| ◆ Lysates | ||
| IL13-1336MCL | Recombinant Mouse IL13 cell lysate | +Inquiry |
| IL13-001HCL | Recombinant Human IL13 cell lysate | +Inquiry |
| IL13-2922HCL | Recombinant Human IL13 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (10)
Ask a question
How does flow cytometry help quantify IL13 receptor expression on different cell populations?
12/29/2022
Flow cytometry quantifies IL13 receptor expression on cells.
What are the benefits of using transgenic animal models to study IL13's in vivo functions?
07/05/2022
Transgenic models illuminate IL13's in vivo functions.
Could you explain the role of ELISA in quantifying IL13 secretion levels in cell cultures?
02/23/2022
ELISA quantifies IL13 secretion in cell cultures accurately.
How can siRNA knockdown experiments reveal IL13's effects on specific cellular processes?
06/13/2021
siRNA knockdown uncovers IL13's specific cellular effects.
How does co-immunoprecipitation identify interacting partners in IL13-mediated signaling complexes?
07/28/2019
Co-immunoprecipitation identifies IL13 signaling partners.
What techniques can differentiate IL13-mediated signaling pathways from IL4 pathways?
07/23/2019
Differential techniques distinguish IL13 and IL4 signaling pathways.
Could you elaborate on the use of reporter gene assays to assess IL13-driven transcriptional activity?
12/16/2018
Reporter gene assays gauge IL13-driven transcription.
Can you describe the applications of microarray analysis in profiling IL13-induced gene expression changes?
11/14/2018
Microarray analysis profiles IL13-induced gene expression.
What experimental methods determine the impact of IL13 on tissue remodeling processes?
08/04/2018
Experimental methods reveal IL13's impact on tissue remodeling.
How does site-directed mutagenesis help identify critical residues in IL13 receptor binding?
07/04/2018
Site-directed mutagenesis identifies key residues in IL13 receptor binding.
Customer Reviews (3)
Write a reviewReviews
11/29/2021
Effective in Th2 cell differentiation. -
04/22/2020
Good for cytokine assays. -
01/26/2019
High yield in expression. -
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