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Recombinant Active Mouse IL1A Protein, His-tagged(C-ter)

Cat.No. : Il1a-158M
Product Overview : Recombinant Active Mouse IL1A Protein with His tag (C-ter) was expressed in E. coli.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
Source : E. coli
Species : Mouse
Tag : His(C-ter)
Form : Powder
Bio-activity : Determined by its ability to induce D10.G4.1 cells proliferation. The ED50 for this effect is < 5 pg/ml. The specific activity of recombinant mouse IL-1 alpha is > 2 x 10^8 IU/mg.
AA Sequence : MSAPYTYQSDLRYKLMKLVRQKFVM NDSLNQTIYQDVDKHYLSTTWLNDL QQEVKFDMYAYSSGGDDSKYPVTLK ISDSQLFVSAQGEDQPVLLKELPET PKLITGSETDLIFFWKSINSKNYFT SAAYPELFIATKEQSRVHLARGLPS MTDFQIS
Endotoxin : Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test.
Purity : > 95% (by SDS-PAGE)
Applications : SDS-PAGE
Notes : For laboratory research only, not for drug, diagnostic or other use.
Storage : Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
Storage Buffer : PBS (pH 7.4)
Reconstitution : It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
Gene Name : Il1a interleukin 1 alpha [ Mus musculus ]
Official Symbol : Il1a
Synonyms : IL1A; interleukin 1 alpha; interleukin-1 alpha; IL-1 alpha; Il-1a;
Gene ID : 16175
mRNA Refseq : NM_010554
Protein Refseq : NP_034684

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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