Active Recombinant Human IL1A

Species :	Human
Source :	Human
Tag :	Non
Description :	Interleukin-1 alpha (IL-1μ) is a protein that in humans is encoded by the IL1A gene. The protein encoded by this gene is a cytokine of the interleukin-1 family. Interleukin-1 alpha possesses a wide spectrum of metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor.
Sequence :	SAPFSFLS NVKYNFMRII KYEFILNDAL NQSIIRANDQ YLTAAALHNL DEAVKFDMGA YKSSKDDAKI TVILRISKTQ LYVTAQDEDQ PVLLKEMPEI PKTITGSETN LLFFWETHGT KNYFTSVAHP NLFIATKQDY WVCLAGGPPS ITDFQILENQ A
Theoretical MW (kDa) :	18
Form :	Lyophilized
Preparation Method :	Escherichia coli expression system
Purity :	> 97% by SDS-PAGE and HPLC
Endotoxin Level :	< 0.1 ng/ug (1 EU/ug)
Activity :	The ED50 was determined by the dose-dependent stimulation of murine D10S cells is μ 0.002 ng/mL, corresponding to a specific activity of μ 2 x 109 units/mg
Application :	SDS-PAGE
Storage Buffer :	Lyophilized from PBS, pH 7.0
Storage :	Store at -20°C on dry atmosphere for 2 years. After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months. Aliquot to avoid repeated freezing and thawing.
Unitprot ID :	P01583
Pathways :	Apoptosis; Cytokine-cytokine receptor interaction; Graft-versus-host disease; Hematopoietic cell lineage; MAPK signaling pathway; Prion diseases; Type I diabetes mellitus

Gene Name	IL1A interleukin 1, alpha [ Homo sapiens ]
Official Symbol	IL1A
Synonyms	IL1A; interleukin 1, alpha; IL1; IL-1A; IL1F1; IL1-ALPHA; preinterleukin 1 alpha; hematopoietin-1; pro-interleukin-1-alpha; Interleukin-1 alpha; IL-1 alpha; Hematopoietin-1; IL1A (IL1F1)
Gene ID	3552
mRNA Refseq	NM_000573
Protein Refseq	NP_000566
MIM	147760
Chromosome Location	2q14
Function	cytokine activity; interleukin-1 receptor binding; protein binding