Recombinant Human ALAS1 Protein, GST-tagged

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Recombinant Human ALAS1 Protein, GST-tagged

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Cat.No. : ALAS1-429H
Product Overview : Human ALAS1 partial ORF ( NP_000679, 1 a.a. - 98 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 36.52 kDa
AA Sequence : MESVVRRCPF LSRVPQAFLQ KAGKSLLFYA QNCPKMMEVG AKPAPRALST AAVHYQQIKE TPPASEKDKT AKAKVQQTPD GSQQSPDGTQ LPSGHPLP
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Figure :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : ALAS1 aminolevulinate, delta-, synthase 1 [ Homo sapiens ]
Official Symbol : ALAS1
Synonyms : ALAS1; aminolevulinate, delta-, synthase 1; ALAS, ALAS3; 5-aminolevulinate synthase, nonspecific, mitochondrial; ALAS-H; delta-ALA synthase 1; migration-inducing protein 4; 5-aminolevulinic acid synthase 1; delta-aminolevulinate synthase 1; ALAS; MIG4; ALAS3; ALASH;
Gene ID : 211
mRNA Refseq : NM_000688
Protein Refseq : NP_000679
MIM : 125290
UniProt ID : P13196
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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