Recombinant Human BRD4 Protein (44-460), N-His tagged
Cat.No. : | BRD4-05H |
Product Overview : | Human recombinant BRD4, tandem construct comprising bromodomains 1 and 2 (residues 44-460; Genbank Accession # NM_058243; MW = 49.7 kDa) expressed in E. coli with an N-terminal His-tag. |
- Specification
- Gene Information
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Description : | The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. |
Source : | E. coli |
Species : | Human |
Tag : | N-His |
Molecular Mass : | 49.7 kDa |
Protein Length : | 44-460 |
Purity : | > 90% by SDS-PAGE |
Storage : | At -80 centigrade, aliquot and snap-freeze after first use. |
Storage Buffer : | Solution of purified recombinant protein in 50 mM Tris/HCl, pH 7.5, 500 mM NaCl, 1.0 mM TCEP, 10% glycerol (v/v) |
Gene Name : | BRD4 bromodomain containing 4 [ Homo sapiens (human) ] |
Official Symbol : | BRD4 |
Synonyms : | BRD4; bromodomain containing 4; CAP; MCAP; HUNK1; HUNKI; FSHRG4; bromodomain-containing protein 4; chromosome-associated protein; female sterile homeotic related gene 4; mitotic chromosome-associated protein; EC 3.1.1.31 |
Gene ID : | 23476 |
mRNA Refseq : | NM_058243 |
Protein Refseq : | NP_490597 |
MIM : | 608749 |
UniProt ID : | O60885 |
Products Types
◆ Recombinant Protein | ||
BRD4-0298H | Recombinant Human BRD4 Protein (S42-E168), His tagged | +Inquiry |
BRD4-0297H | Recombinant Human BRD4 Protein (S42-E168), Tag Free | +Inquiry |
BRD4-35H | Active Recombinant Human BRD4 (BD1) Protein (49-170), N-His tagged | +Inquiry |
BRD4-2559H | Recombinant Human BRD4 Protein, His (Fc)-Avi-tagged | +Inquiry |
BRD4-38H | Active Recombinant Human BRD4 (BD2) Protein (342-460), N-His tagged | +Inquiry |
◆ Lysates | ||
BRD4-179HCL | Recombinant Human BRD4 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1697 | BRD4 (BD1) TR-FRET Assay Kit | +Inquiry |
Kit-1696 | BRD4 (BD1) Inhibitor Screening Assay Kit | +Inquiry |
Kit-1698 | BRD4 (BD1+BD2) TR-FRET Assay Kit | +Inquiry |
Kit-1699 | BRD4 (BD2) Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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