Recombinant Human BRD4 Protein (44-460), N-His tagged

Cat.No. : BRD4-05H
Product Overview : Human recombinant BRD4, tandem construct comprising bromodomains 1 and 2 (residues 44-460; Genbank Accession # NM_058243; MW = 49.7 kDa) expressed in E. coli with an N-terminal His-tag.
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Description : The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Source : E. coli
Species : Human
Tag : His
Molecular Mass : 49.7 kDa
Protein Length : 44-460
Purity : > 90% by SDS-PAGE
Storage : At -80 centigrade, aliquot and snap-freeze after first use.
Storage Buffer : Solution of purified recombinant protein in 50 mM Tris/HCl, pH 7.5, 500 mM NaCl, 1.0 mM TCEP, 10% glycerol (v/v)
Gene Name : BRD4 bromodomain containing 4 [ Homo sapiens (human) ]
Official Symbol : BRD4
Synonyms : BRD4; bromodomain containing 4; CAP; MCAP; HUNK1; HUNKI; FSHRG4; bromodomain-containing protein 4; chromosome-associated protein; female sterile homeotic related gene 4; mitotic chromosome-associated protein; EC 3.1.1.31
Gene ID : 23476
mRNA Refseq : NM_058243
Protein Refseq : NP_490597
MIM : 608749
UniProt ID : O60885

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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