Active Recombinant Human BRD4 (BD2) Protein (342-460), N-His tagged

Cat.No. : BRD4-38H
Product Overview : Active Recombinant human BRD4 (BD2) (342-460) was expressed in E. coli cells using an N-terminal His tag.
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  • Gene Information
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Description : Bromodomain-containing protein 4 (BRD4) is a member of the bromodomain and extra-terminal domain (BET) protein family. BRD4 contains two tandem bromodomains: BD1 and BD2. BRD4 (BD2) interacts with acetylated histones and other transcription factors, influencing the assembly and stability of large transcriptional complexes at specific genomic loci. It serves as a scaffold for the recruitment of various coregulatory proteins, contributing to the activation or repression of target genes. BRD4 (BD2) plays a critical role in cell cycle progression, as well as the maintenance of pluripotency and self-renewal in embryonic stem cells.
Source : E. coli
Species : Human
Tag : N-His
Bio-activity : 531 ng/min/mg
Molecular Mass : Observed MW: ~14 kDa
Calculated MW: ~14.3 kDa
Protein Length : 342-460
Purity : > 90%
Stability : One year at –70 centigrade from date of shipment.
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1 μg/μL
Storage Buffer : Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.25mM DTT, 25% glycerol.
Shipping : Dry ice
Gene Name : BRD4 bromodomain containing 4 [ Homo sapiens (human) ]
Official Symbol : BRD4
Synonyms : BRD4; bromodomain containing 4; bromodomain-containing protein 4; CAP; chromosome associated protein; HUNK1; HUNKI; MCAP; bromodomain-containing 4; chromosome-associated protein;
Gene ID : 23476
mRNA Refseq : NM_014299
Protein Refseq : NP_055114
MIM : 608749
UniProt ID : O60885

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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