Recombinant Human BTC Protein, Fc-tagged

• Cat.No.: BTC-106H
• Product Overview: Recombinant human BTC protein with Fc tag was expressed in HEK293.

Specification

• Description: This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.
• Source: HEK293
• Species: Human
• Tag: Fc
• Form: Lyophilized
• Molecular Mass: 36.5 kDa
• Protein length: 178
• AA Sequence: MDRAARCSGASSLPLLLALALGLVI LHCVVADGNSTRSPETNGLLCGDPE ENCAATTTQSKRKGHFSRCPKQYKH YCIKGRCRFVVAEQTPSCVCDEGYI GARCERVDLFYLRGDRGQILVICLI AVMVVFIILVIGVCTCCHPLRKRRK RKKKEEEMETLGKDITPINEDIEET NIA
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: BTC betacellulin [ Homo sapiens (human) ]
• Official Symbol: BTC
• Synonyms: BTC; betacellulin; probetacellulin
• Gene ID: 685
• mRNA Refseq: NM_001729
• Protein Refseq: NP_001720
• MIM: 600345
• UniProt ID: P35070

Reviews

12/16/2022

Because of its high activity, few experiments were successful, reducing the number of our experiments.

08/08/2021

High cost performance, affordable price, good experimental effect.

01/30/2021

Excellent product, perfect for western-blot.

Q&As

Does BTC protein have potential in the treatment of metabolic diseases?

Yes, BTC protein is involved in both energy metabolism and fat metabolism, so it has some potential in the treatment of metabolic diseases.

How about BTC protein have an effect on nervous system development and function?

This protein has a role in the development and function of the nervous system to control the differentiation and growth of neurons.

What is the role of BTC protein in wound repair?

BTC protein can promote cell proliferation, pocket sac (D472250) and microvascular growth, etc., and plays an important role in wound healing and repair.

Does BTC protein have a role in PTSD treatment?

This protein plays a regulatory role in the pathogenesis and treatment mechanism of PTSD, and is one of the new targets for the treatment of Wolverine poisoning.

What is the role of BTC protein in osteoporosis?

It is involved in the occurrence and process of osteoporosis, and related research has become an important breakthrough in the treatment of osteoporosis.

What is the role of BTC protein in organ transplant rejection?

BTC is involved in the occurrence and process of organ transplant rejection and has become one of the targets for the treatment of transplant rejection.