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Recombinant Human CCL5 Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | CCL5-2625H |
| Product Overview : | CCL5 MS Standard C13 and N15-labeled recombinant protein (NP_002976) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 10 kDa |
| AA Sequence : | MKVSAAALAV ILIATALCAP ASASPYSSDT TPCCFAYIAR PLPRAHIKEY FYTSGKCSNP AVVFVTRKNR QVCANPEKKW VREYINSLEM STRTRPLEQK LISEEDLAAN DILDYKDDDD KV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | CCL5 C-C motif chemokine ligand 5 [ Homo sapiens (human) ] |
| Official Symbol : | CCL5 |
| Synonyms : | CCL5; chemokine (C-C motif) ligand 5; D17S136E, SCYA5, small inducible cytokine A5 (RANTES); C-C motif chemokine 5; beta chemokine RANTES; MGC17164; RANTES; regulated upon activation; normally T expressed; and presumably secreted; SIS delta; SISd; small inducible cytokine subfamily A (Cys Cys); member 5; T cell specific protein p288; T cell specific RANTES protein; TCP228; eoCP; SIS-delta; beta-chemokine RANTES; small-inducible cytokine A5; T-cell specific protein p288; t cell-specific protein P228; T-cell-specific protein RANTES; eosinophil chemotactic cytokine; small inducible cytokine A5 (RANTES); small inducible cytokine subfamily A (Cys-Cys), member 5; regulated upon activation, normally T-expressed, and presumably secreted; SCYA5; D17S136E; |
| Gene ID : | 6352 |
| mRNA Refseq : | NM_002985 |
| Protein Refseq : | NP_002976 |
| MIM : | 187011 |
| UniProt ID : | P13501 |
◆ Recombinant Protein
| CCL5-4354S | Recombinant Swine CCL5 Protein | +Inquiry |
| CCL5-4397C | Recombinant Cynomolgus Monkey CCL5 Protein | +Inquiry |
| Ccl5-2040M | Recombinant Mouse Ccl5 Protein, Myc/DDK-tagged | +Inquiry |
| CCL5-312R | Recombinant Rat CCL5 Protein, His-tagged | +Inquiry |
| CCL5-4353R | Recombinant Rabbit CCL5 Protein | +Inquiry |
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◆ Lysates
| CCL5-2706HCL | Recombinant Human CCL5 cell lysate | +Inquiry |
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CCL1CCL11Ccl12CCL13CCL14CCL15CCL16CCL17CCL18CCL19CCL2CCL20CCL21Ccl21cCCL22CCL23CCL24CCL25CCL26CCL27Ccl27aCCL28CCL3CCL3L1Ccl4CCL5Ccl6CCL7CCL8Ccl9CCL4L2Ccl21aCCL4L1CCL3L3Ccl21bCcl27b
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