Recombinant Human CD33, His-tagged
Cat.No. : | CD33-5088H |
Product Overview : | Recombinant human CD33 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | CD33 is putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. This protein induces apoptosis in acute myeloid leukemia (in vitro). |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol |
Molecular Mass : | 29.1 kDa (265aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSDPNFWLQ VQESVTVQEG LCVLVPCTFF HPIPYYDKNS PVHGYWFREG AIISGDSPVA TNKLDQEVQE ETQGRFRLLG DPSRNNCSLS IVDARRRDNG SYFFRMERGS TKYSYKSPQL SVHVTDLTHR PKILIPGTLE PGHSKNLTCS VSWACEQGTP PIFSWLSAAP TSLGPRTTHS SVLIITPRPQ DHGTNLTCQV KFAGAGVTTE RTIQLNVTYV PQNPTTGIFP GDGSGKQETR AGVVH |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | CD33 CD33 molecule [ Homo sapiens ] |
Official Symbol : | CD33 |
Synonyms : | CD33; CD33 molecule; CD33 antigen (gp67); myeloid cell surface antigen CD33; FLJ00391; p67; sialic acid binding Ig like lectin 3; SIGLEC 3; SIGLEC3; gp67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC-3; |
Gene ID : | 945 |
mRNA Refseq : | NM_001082618 |
Protein Refseq : | NP_001076087 |
MIM : | 159590 |
UniProt ID : | P20138 |
Chromosome Location : | 19q13.3 |
Pathway : | Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; |
Function : | receptor activity; sugar binding; |
Products Types
◆ Recombinant Protein | ||
CD33-240H | Recombinant Human CD33 Protein, hIgG-His-tagged | +Inquiry |
CD33-551H | Recombinant Human CD33 Protein (Met1-His259) | +Inquiry |
Cd33-5169M | Recombinant Mouse Cd33 protein(Met1-Glu240), His-tagged | +Inquiry |
CD33-3097H | Recombinant Human CD33 Protein, MYC/DDK-tagged | +Inquiry |
CD33-26H | Active Recombinant Human CD33 Protein, Fc-tagged, Alexa Fluor® 647 conjugated | +Inquiry |
◆ Lysates | ||
CD33-1808MCL | Recombinant Mouse CD33 cell lysate | +Inquiry |
CD33-978HCL | Recombinant Human CD33 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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