Recombinant Human CD8B Protein, C-His-tagged
Cat.No. : | CD8B-177H |
Product Overview : | Recombinant Human CD8B Protein with C-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The T cell receptor (TCR) is a heterodimer composed of either a and b or γ and δ chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8. T helper cells express CD4 proteins and T cytotoxic cells display CD8. CD8 (also designated Leu 2 or T8), a cell surface glycoprotein, is a two chain complex (aa or ab) receptor that binds class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression. |
Source : | E. coli |
Species : | Human |
Tag : | C-His |
Molecular Mass : | ~16 kDa |
AA Sequence : | LQQTPAYIKVQTNKMVMLSCEAKIS LSNMRIYWLRQRQAPSSDSHHEFLA LWDSAKGTIHGEEVEQEKIAVFRDA SRFILNLTSVKPEDSGIYFCMIVGS PELTFGKGTQLSVVDFLPTTAQPTK KSTLKKRVCRLPRPETQKGPLCSP |
Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
Concentration : | ≥0.5 mg/mL |
Storage Buffer : | PBS, 4M Urea, pH7.4 |
Gene Name : | CD8B CD8b molecule [ Homo sapiens (human) ] |
Official Symbol : | CD8B |
Synonyms : | CD8B; CD8b molecule; CD8 antigen, beta polypeptide 1 (p37) , CD8B1; T-cell surface glycoprotein CD8 beta chain; CD8 antigen, beta polypeptide 1 (p37); T lymphocyte surface glycoprotein beta chain; LY3; P37; LEU2; LYT3; CD8B1; MGC119115; |
Gene ID : | 926 |
mRNA Refseq : | NM_001178100 |
Protein Refseq : | NP_001171571 |
MIM : | 186730 |
UniProt ID : | P10966 |
Products Types
◆ Recombinant Protein | ||
CD8B-923R | Recombinant Rat CD8B Protein, His (Fc)-Avi-tagged | +Inquiry |
CD8B-479H | Recombinant Human CD8B Protein (Met1-Pro170), Biotinylated | +Inquiry |
CD8B-707R | Recombinant Rabbit CD8B Protein, His&GST-tagged | +Inquiry |
CD8B-26H | Recombinant Human CD8B Protein, His-tagged | +Inquiry |
CD8B-0880H | Recombinant Human CD8B Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
CD8B-001HCL | Recombinant Human CD8B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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