Recombinant Human CD8B Protein, GST-Tagged

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Recombinant Human CD8B Protein, GST-Tagged

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Cat.No. : CD8B-0880H
Product Overview : Human CD8B1 full-length ORF (NP_757362.1, 1 a.a. - 243 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 53.6 kDa
AA Sequence : MRPRLWLLLA AQLTVLHGNS VLQQTPAYIK VQTNKMVMLS CEAKISLSNM RIYWLRQRQA PSSDSHHEFL ALWDSAKGTI HGEEVEQEKI AVFRDASRFI LNLTSVKPED SGIYFCMIVG SPELTFGKGT QLSVVDFLPT TAQPTKKSTL KKRVCRLPRP ETQKGPLCSP ITLGLLVAGV LVLLVSLGVA IHLCCRRRRA RLRFMKQPQG EGISGTFVPQ CLHGYYSNTT TSQKLLNPWI LKT
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CD8B CD8b molecule [ Homo sapiens ]
Official Symbol : CD8B
Synonyms : CD8B; CD8b molecule; CD8 antigen, beta polypeptide 1 (p37), CD8B1; T-cell surface glycoprotein CD8 beta chain; CD8 antigen, beta polypeptide 1 (p37); T lymphocyte surface glycoprotein beta chain; LY3; P37; LEU2; LYT3; CD8B1; MGC119115;
Gene ID : 926
mRNA Refseq : NM_001178100
Protein Refseq : NP_001171571
MIM : 186730
UniProt ID : P10966

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