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Official Full Name CD8b molecule
Background CD8b antigen is also known as T8, Lyt2, Ly-2, and CD8beta. It is a member of the immunoglobulin superfamily expressed on most thymocytes, some mature T cell subsets, and macrophages. CD8b forms heterodimers with the CD8alpha chain (CD8a). CD8 is an antige
Synonyms CD8B; CD8b molecule; CD8 antigen, beta polypeptide 1 (p37) , CD8B1; T-cell surface glycoprotein CD8 beta chain; CD8 antigen, beta polypeptide 1 (p37); T lymphocyte surface glycoprotein beta chain; LY3; P37; LEU2; LYT3; CD8B1; MGC119115
    • Species :
    • Chicken
    • Human
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Human Cells
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CD8B-151H Recombinant Human CD8B Protein, His-tagged Human Cells His
    Human CD8B-001HCL Recombinant Human CD8B cell lysate Human Cell N/A
    Human CD8B-0880H Recombinant Human CD8B Protein, GST-Tagged Wheat Germ GST
    Human CD8B-10983H Recombinant Human CD8B, GST-tagged E.coli GST
    Human CD8B-209H Recombinant Human CD8B Protein, His-tagged HEK293 His
    Human CD8B-253H Recombinant Human CD8B Human Cell N/A
    Human CD8B-26H Recombinant Human CD8B Protein, His-tagged HEK293 His
    Human CD8B-270H Recombinant Human CD8B Protein, Fc-tagged HEK293 Fc
    Human CD8B-27892TH Recombinant Human CD8B Wheat Germ N/A
    Human CD8B-423H Recombinant Human CD8b molecule, His-tagged E.coli His
    Human CD8B-479H Recombinant Human CD8B Protein (Met1-Pro170), Biotinylated HEK293 N/A
    Human CD8B-5024H Recombinant Human CD8B, His-tagged E.coli His
    Rat CD8B-1265R Recombinant Rat CD8B Protein Mammalian Cell His
    Rat Cd8b-1529R Recombinant Rat Cd8b protein, His-tagged E.coli His
    Chicken CD8B-6799C Recombinant Chicken CD8B Mammalian Cell His

    cd8b involved in several pathways and played different roles in them. We selected most pathways cd8b participated on our site, such as Cell adhesion molecules (CAMs), Antigen processing and presentation, Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with cd8b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell adhesion molecules (CAMs) CLDN11A; CLDNF; VCAN; HLA-B; CLDN14; PTPRF; JAM3; ALCAM; CD40; NLGN2
    Antigen processing and presentation PDIA3; KIR2DL3; TAP1; HLA-DRB5; HLA-DPB1; KLRC2; TAPBP; CTSL1; HLA-DOB; KIR3DL1
    Hematopoietic cell lineage HLA-DRB3; CD22; Itga10&Itgb1; IL7R; KIT; ITGA5; FLT3; GYPA; GP9; HLA-DRB1
    T cell receptor signaling pathway TEC; VAV1; DBNLB; PAK3; NFATC1; IL5; GRB2; MAPK13; IL4; ICOS
    Primary i TAP2; RAG2; RFXANK; AICDA; RFX5; IGLL1; ZAP70; CD8A; CD8B1; CD3E
    nodeficiency CD4; CD8A; CD40; TAP1; ZAP70; RFX5; UNG; CD3E; ICOS; CD19

    cd8b has several biochemical functions, for example, MHC class I protein binding, coreceptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cd8b itself. We selected most functions cd8b had, and list some proteins which have the same functions with cd8b. You can find most of the proteins on our site.

    Function Related Protein
    MHC class I protein binding PILRB2; HLA-E; TAPBP; DERL1; BCAP31; ATP5B; PILRB; LILRB1; TUBB; CD8A
    coreceptor activity RAMP2; RGMB; CXCR6; HFE2; IGSF1; PVRL2; CD8B; CD4; CXCR7B; RGMD
    protein binding ESYT1; MSLN; PIN4; SORL1; ITM2B; TXLNG; PKP1; SMURF2; ITGA6; BCL2

    cd8b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cd8b here. Most of them are supplied by our site. Hope this information will be useful for your research of cd8b.

    Cooney, LA; Gupta, M; et al. Short-Lived Effector CD8 T Cells Induced by Genetically Attenuated Malaria Parasite Vaccination Express CD11c. INFECTION AND IMMUNITY 81:4171-4181(2013).
    Clement, M; Ladell, K; et al. Anti-CD8 Antibodies Can Trigger CD8(+) T Cell Effector Function in the Absence of TCR Engagement and Improve Peptide-MHCI Tetramer Staining. JOURNAL OF IMMUNOLOGY 187:654-663(2011).

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