CD8B

  • Official Full Name

    CD8b molecule

  • Overview

    CD8b antigen is also known as T8, Lyt2, Ly-2, and CD8beta. It is a member of the immunoglobulin superfamily expressed on most thymocytes, some mature T cell subsets, and macrophages. CD8b forms heterodimers with the CD8alpha chain (CD8a). CD8 is an antige
  • Synonyms

    CD8B; CD8b molecule; CD8 antigen, beta polypeptide 1 (p37) , CD8B1; T-cell surface glycoprotein CD8 beta chain; CD8 antigen, beta polypeptide 1 (p37); T lymphocyte surface glycoprotein beta chain; LY3; P37; LEU2; LYT3; CD8B1; MGC119115;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus
  • Felis catus (Cat) (Felis silvestris catus)
  • Homo sapiens (Human)
  • Human
  • Mus musculus (Mouse)
  • Pongo pygmaeus (Bornean orangutan)
  • Rabbit
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • Human Cells
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • Fc
  • His
  • GST
  • hFc
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD8B-27892TH Recombinant Human CD8B Wheat Germ N/A 243 amino acids
Human CD8B-423H Recombinant Human CD8b molecule, His-tagged E.coli His
Human CD8B-10983H Recombinant Human CD8B, GST-tagged E.coli GST 22-171a.a.
Human CD8B-5024H Recombinant Human CD8B, His-tagged E.coli His
Human CD8B-253H Recombinant Human CD8B Human Cell N/A Met1-Pro170
Human CD8B-270H Recombinant Human CD8B Protein, Fc-tagged HEK293 Fc
Human CD8B-209H Recombinant Human CD8B Protein, His-tagged HEK293 His Leu22-Pro170
Human CD8B-0880H Recombinant Human CD8B Protein, GST-Tagged Wheat Germ GST
Human CD8B-001HCL Recombinant Human CD8B cell lysate Human Cell N/A
Human CD8B-26H Recombinant Human CD8B Protein, His-tagged HEK293 His
Human CD8B-3819H Recombinant Human CD8B protein, His-tagged E.coli His 22-171 aa
Human CD8B-479H Recombinant Human CD8B Protein (Met1-Pro170), Biotinylated HEK293 N/A Met1-Pro170
Human CD8B-151H Recombinant Human CD8B Protein, His-tagged Human Cells His
Human CD8B-0970H Recombinant Human CD8B Protein (Leu22-Pro170), N-His tagged E.coli N-His Leu22-Pro170
Human CD8B-3091HF Recombinant Full Length Human CD8B Protein, GST-tagged In Vitro Cell Free System GST 243 amino acids
Human CD8B-65HF Recombinant Full Length Human CD8B Protein In Vitro Cell Free System 243 amino acids
Human CD8B-177H Recombinant Human CD8B Protein, C-His-tagged E.coli C-His
Human CD8B-5305H Recombinant Human CD8B Protein (Met1-Pro170), C-Fc tagged Mammalian cells C-Fc Met1-Pro170
Human CD8B-5306H Recombinant Human CD8B Protein (Met1-Pro170), C-His tagged Mammalian cells C-His Met1-Pro170
Human CD8B-1042H Recombinant Human CD8B protein(Met1-Pro170), Biotinylated HEK293 N/A Met1-Pro170
Rat CD8B-1265R Recombinant Rat CD8B Protein Mammalian Cell His
Rat CD8B-923R Recombinant Rat CD8B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Cd8b-1529R Recombinant Rat Cd8b protein, His-tagged E.coli His Ala21~Lys208
Rat CD8B-923R-B Recombinant Rat CD8B Protein Pre-coupled Magnetic Beads HEK293
Rabbit CD8B-707R Recombinant Rabbit CD8B Protein, His&GST-tagged E.coli N-His&GST Ser19-Arg206
Cynomolgus CD8B-0880C Recombinant Cynomolgus CD8B protein, hFc-tagged HEK293 hFc Met1-Pro170
Felis catus (Cat) (Felis silvestris catus) RFL31424FF Recombinant Full Length Cat T-Cell Surface Glycoprotein Cd8 Beta Chain(Cd8B) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (22-210)
Homo sapiens (Human) RFL18691HF Recombinant Full Length Human T-Cell Surface Glycoprotein Cd8 Beta Chain(Cd8B) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (22-210)
Mus musculus (Mouse) RFL19252MF Recombinant Full Length Mouse T-Cell Surface Glycoprotein Cd8 Beta Chain(Cd8B) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (22-213)
Pongo pygmaeus (Bornean orangutan) RFL22738PF Recombinant Full Length Pongo Pygmaeus T-Cell Surface Glycoprotein Cd8 Beta Chain(Cd8B) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (22-210)
Rattus norvegicus (Rat) RFL10801RF Recombinant Full Length Rat T-Cell Surface Glycoprotein Cd8 Beta Chain(Cd8B) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (22-208)
Chicken CD8B-6799C Recombinant Chicken CD8B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CD8B involved in several pathways and played different roles in them. We selected most pathways CD8B participated on our site, such as Cell adhesion molecules (CAMs), Antigen processing and presentation, Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD8B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell adhesion molecules (CAMs)NFASC;ITGA8;Siglec1;CLDN8;CLDN17;H2-Q10;ALCAM;CLDN7A;PTPRM
Antigen processing and presentationPSME1;PDIA3;HLA-G;HSPA1L;KIR2DL4;HLA-E;CD8B;HLA-DOA;CTSS
Hematopoietic cell lineageGYPA;CD2;CR2;CD1D;IL3;Itga10&Itgb1;IL5RA;ITGA4;FCGR1A
T cell receptor signaling pathwayGRAP2;RAF1;MAP2K7;MAPK11;PIK3CA;KRAS;TEC;CBLC;Il2
Primary iDCLRE1C;RFXANK;LCK;IGLL1;TNFRSF13B;RFXAP;ORAI1;CD79A;AIRE
nodeficiencyTNFRSF13B;AICDA;CD79A;RFXAP;CD40LG;CD40;UNG;IKBKG;CD8B1

CD8B has several biochemical functions, for example, MHC class I protein binding, coreceptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD8B itself. We selected most functions CD8B had, and list some proteins which have the same functions with CD8B. You can find most of the proteins on our site.

Function Related Protein
MHC class I protein bindingLILRB2;Pilrb1;CD244;TUBB4B;ATP5A1;TUBB;PILRB2;DERL1;TAP1
coreceptor activityCXCR7B;IGSF1;RAMP2;RAMP3;RAMP1;CD80;CD4;PVRL2;CCR5
protein bindingUQCRH;BLK;C16orf72;COPS2;STX4A;ALDOB;ANKS4B;TTYH2;NAB2

CD8B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD8B here. Most of them are supplied by our site. Hope this information will be useful for your research of CD8B.

Research Area

Related articles

Cooney, LA; Gupta, M; et al. Short-Lived Effector CD8 T Cells Induced by Genetically Attenuated Malaria Parasite Vaccination Express CD11c. INFECTION AND IMMUNITY 81:4171-4181(2013).
Clement, M; Ladell, K; et al. Anti-CD8 Antibodies Can Trigger CD8(+) T Cell Effector Function in the Absence of TCR Engagement and Improve Peptide-MHCI Tetramer Staining. JOURNAL OF IMMUNOLOGY 187:654-663(2011).
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