Recombinant Full Length Human CD8B Protein, GST-tagged

Cat.No. : CD8B-3091HF
Product Overview : Human CD8B1 full-length ORF (NP_757362.1, 1 a.a. - 243 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
Source : In Vitro Cell Free System
Species : Human
Tag : GST
Molecular Mass : 53.6 kDa
Protein Length : 243 amino acids
AA Sequence : MRPRLWLLLAAQLTVLHGNSVLQQT PAYIKVQTNKMVMLSCEAKISLSNM RIYWLRQRQAPSSDSHHEFLALWDS AKGTIHGEEVEQEKIAVFRDASRFI LNLTSVKPEDSGIYFCMIVGSPELT FGKGTQLSVVDFLPTTAQPTKKSTL KKRVCRLPRPETQKGPLCSPITLGL LVAGVLVLLVSLGVAIHLCCRRRRA RLRFMKQPQGEGISGTFVPQCLHGY YSNTTTSQKLLNPWILKT
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CD8B CD8b molecule [ Homo sapiens ]
Official Symbol : CD8B
Synonyms : CD8B; CD8b molecule; CD8 antigen, beta polypeptide 1 (p37), CD8B1; T-cell surface glycoprotein CD8 beta chain; CD8 antigen, beta polypeptide 1 (p37); T lymphocyte surface glycoprotein beta chain; LY3; P37; LEU2; LYT3; CD8B1; MGC119115;
Gene ID : 926
mRNA Refseq : NM_001178100
Protein Refseq : NP_001171571
MIM : 186730
UniProt ID : P10966

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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