CCL3-156H
Optional Service: Optional requirements on this protein
Product Overview :
Recombinant human chemokine (C-C motif) ligand 3 was expressed inSf21 cells.
Description :
Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP-1α and MIP-1β that are now officially named CCL3 and CCL4 respectively. Both are major factors produced by macrophages after they are stimulated with bacterial endotoxins. They activate human granulocytes (neutrophils, eosinophils and basophils) which can lead to acute neutrophilic inflammation. They also induce the synthesis and release of other pro-inflammatory cytokines such as interleukin 1 (IL-1), IL-6 and TNF-α from fibroblasts and macrophages. The genes for CCL3 and CCL4 are both located on human chromosome 17.
Source :
Sf21 cells.
Analysis Note :
The biological activity is measured by its ability to chemoattract cultured human monocytes or mouse BaF/3 cells transfected with human CCR5.
Physical Form :
Lyophilized from a 0.2 μm filtered solution of 30% acetonitrile and 0.1% trifluoroacetic acid containing 0.5 mg bovine serum albumin.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.