Recombinant Human CCL3, His-tagged CCL3-29859TH

Recombinant Human CCL3, His-tagged

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Recombinant Human CCL3, His-tagged

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Cat.No. : CCL3-29859TH Optional Service: Optional requirements on this protein
Product Overview : Recombinant full length Human Macrophage Inflammatory Protein 1 alpha / CCL3 with N terminal His tag; 90 amino acids with tag, Predicted MWt 10 kDa.
Description : This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.
Protein length : 69 amino acids
Conjugation : HIS
Molecular Weight : 10.000kDa inclusive of tags
Source : E. coli
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 10% Glycerol, 10mM Sodium citrate, pH 3.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MSLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA
Sequence Similarities : Belongs to the intercrine beta (chemokine CC) family.
Gene Name : CCL3 chemokine (C-C motif) ligand 3 [ Homo sapiens ]
Official Symbol : CCL3
Synonyms : CCL3; chemokine (C-C motif) ligand 3; SCYA3, small inducible cytokine A3 (homologous to mouse Mip 1a); C-C motif chemokine 3; G0S19 1; LD78ALPHA; MIP 1 alpha;
Gene ID : 6348
mRNA Refseq : NM_002983
Protein Refseq : NP_002974
MIM : 182283
Uniprot ID : P10147
Chromosome Location : 17q12
Pathway : Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem;
Function : chemoattractant activity; chemokine activity; signal transducer activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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