Recombinant Human chemokine (C-C motif) ligand 5, His-tagged
Cat.No. : | CCL5-61H |
Product Overview : | Recombinant Human CCL5 comprises a 68 amino acid fragment (24-91) corresponding to the mature RANTES protein and is expressed in E. coli with an amino-terminal hexahistidine tag. |
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Cat. No. : | CCL5-61H |
Description : | CCL5 (acronym for Regulated upon Activation, Normal T-cell Expressed, and presumably Secreted) is a member of the beta (CC) chemokine subfamily and is predominantly produced from T cells and platelets. RANTES has been shown to be a chemoattractant factor for monocytes, CD4+/CD45RO+ T lymphocytes and basophils. It has also been shown to induce the proliferation and activation of killer cells and may act as a HIV suppressive factor. |
Source : | E.coli. |
Purity : | >95% by SDS-PAGE |
Form : | Liquid |
Storage : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
Protein length : | 24-91 |
Gene Name : | CCL5 chemokine (C-C motif) ligand 5 [ Homo sapiens ] |
Synonyms : | CCL5; D17S136E; MGC17164; RANTES; SCYA5; SISd; TCP228; chemokine (C-C motif) ligand 5; small inducible cytokine A5; SIS-delta; beta-chemokine RANTES; T-cell specific protein p288; T-cell specific RANTES protein; small inducible cytokine A5 (RANTES); small inducible cytokine subfamily A (Cys-Cys), member 5; regulated upon activation, normally T-expressed, and presumably secreted; CCL5; Chemokine (C-C motif) ligand 5; T-cell specific RANTES protein; T-cell; specific protein P288; beta chemokine RANTES precursor; SIS delta; EoCP; Eosinophil-chemotactic cytokine; T-cell specific RANTES protein; T-cell-specific protein RANTES; small inducible cytokine A5. |
Gene ID : | 6352 |
mRNA Refseq : | NM_002985 |
Protein Refseq : | NP_002976 |
MIM : | 187011 |
UniProt ID : | P13501 |
Chromosome Location : | 17q11.2-q12 |
Pathway : | Cytokine-cytokine receptor interaction; Epithelial cell signaling in Helicobacter pylori infection; Toll-like receptor signaling pathway; :Signaling by GPCR |
Function : | chemoattractant activity; chemokine activity; signal transducer activity |
Products Types
◆ Recombinant Protein | ||
CCL5-059C | Active Recombinant Human CCL5 Protein (68 aa) | +Inquiry |
Ccl5-29M | Active Recombinant Mouse/Rat CCL5 Protein | +Inquiry |
Ccl5-133M | Active Recombinant Mouse Ccl5 Protein | +Inquiry |
Ccl5-30M | Active Recombinant Mouse/Rat CCL5 Protein | +Inquiry |
CCL5-4397C | Recombinant Cynomolgus Monkey CCL5 Protein | +Inquiry |
◆ Lysates | ||
CCL5-2706HCL | Recombinant Human CCL5 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewThis specificity enables precise quantification and characterization of CCL5 and its interactions with other molecules or proteins of interest.
Its exceptional performance, coupled with its ability to generate clear and precise protein bands, make it an indispensable tool in achieving accurate and reliable results.
The CCL5 protein exhibits a high degree of specificity in various assays, ensuring accurate and reliable results.
Q&As (5)
Ask a questionCCL5 inhibitors may be used to control inflammation in diseases like rheumatoid arthritis or as an adjuvant in cancer therapy.
CCL5-based immunotherapies are being explored to enhance the immune response against cancer cells.
It can serve as a biomarker for some diseases, but it is usually used in conjunction with other markers for more accurate diagnostics.
Elevated CCL5 levels are associated with inflammation and may be indicative of certain diseases such as rheumatoid arthritis or HIV infection.
Yes, there are ongoing efforts to develop therapies that modulate CCL5 activity, particularly in diseases involving inflammation.
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