Recombinant Human CRK Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | CRK-6643H |
Product Overview : | CRK MS Standard C13 and N15-labeled recombinant protein (NP_058431) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 33.8 kDa |
AA Sequence : | MAGNFDSEERSSWYWGRLSRQEAVA LLQGQRHGVFLVRDSSTSPGDYVLS VSENSRVSHYIINSSGPRPPVPPSP AQPPPGVSPSRLRIGDQEFDSLPAL LEFYKIHYLDTTTLIEPVSRSRQGS GVILRQEEAEYVRALFDFNGNDEED LPFKKGDILRIRDKPEEQWWNAEDS EGKRGMIPVPYVEKYRPASASVSAL IGGNQEGSHPQPLGGPEPGPYAQPS VNTPLPNLQNGPIYARVIQKRVPNA YDKTALALEVGELVKVTKINVSGQW EGECNGKRGHFPFTHVRLLDQQNPD EDFSTRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | CRK CRK proto-oncogene, adaptor protein [ Homo sapiens (human) ] |
Official Symbol : | CRK |
Synonyms : | CRK; v-crk sarcoma virus CT10 oncogene homolog (avian); v crk avian sarcoma virus CT10 oncogene homolog; adapter molecule crk; proto-oncogene c-Crk; p38; CRKII; FLJ38130; |
Gene ID : | 1398 |
mRNA Refseq : | NM_016823 |
Protein Refseq : | NP_058431 |
MIM : | 164762 |
UniProt ID : | P46108 |
Products Types
◆ Recombinant Protein | ||
CRK-1886H | Recombinant Human CRK Protein, GST-tagged | +Inquiry |
Crk-2313M | Recombinant Mouse Crk Protein, Myc/DDK-tagged | +Inquiry |
CRK-1260R | Recombinant Rat CRK Protein, His (Fc)-Avi-tagged | +Inquiry |
CRK-661H | Recombinant Human CRK Protein, His (Fc)-Avi-tagged | +Inquiry |
CRK-1603R | Recombinant Rat CRK Protein | +Inquiry |
◆ Lysates | ||
CRK-7276HCL | Recombinant Human CRK 293 Cell Lysate | +Inquiry |
CRK-7277HCL | Recombinant Human CRK 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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