Recombinant Human CRK Protein, GST-tagged
Cat.No. : | CRK-1886H |
Product Overview : | Human CRK full-length ORF ( NP_005197.3, 1 a.a. - 204 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 49.3 kDa |
AA Sequence : | MAGNFDSEERSSWYWGRLSRQEAVA LLQGQRHGVFLVRDSSTSPGDYVLS VSENSRVSHYIINSSGPRPPVPPSP AQPPPGVSPSRLRIGDQEFDSLPAL LEFYKIHYLDTTTLIEPVSRSRQGS GVILRQEEAEYVRALFDFNGNDEED LPFKKGDILRIRDKPEEQWWNAEDS EGKRGMIPVPYVEKYRPASASVSAL IGGR |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CRK CRK proto-oncogene, adaptor protein [ Homo sapiens (human) ] |
Official Symbol : | CRK |
Synonyms : | CRK; CRK CRK proto-oncogene, adaptor protein; v-crk sarcoma virus CT10 oncogene homolog (avian); v crk avian sarcoma virus CT10 oncogene homolog; adapter molecule crk; proto-oncogene c-Crk; p38; CRKII; FLJ38130; |
Gene ID : | 1398 |
mRNA Refseq : | NM_005206 |
Protein Refseq : | NP_005197 |
MIM : | 164762 |
UniProt ID : | P46108 |
Products Types
◆ Recombinant Protein | ||
Crk-2313M | Recombinant Mouse Crk Protein, Myc/DDK-tagged | +Inquiry |
CRK-661H | Recombinant Human CRK Protein, His (Fc)-Avi-tagged | +Inquiry |
CRK-1260R | Recombinant Rat CRK Protein, His (Fc)-Avi-tagged | +Inquiry |
CRK-1053Z | Recombinant Zebrafish CRK | +Inquiry |
CRK-11582H | Recombinant Human CRK, GST-tagged | +Inquiry |
◆ Lysates | ||
CRK-7276HCL | Recombinant Human CRK 293 Cell Lysate | +Inquiry |
CRK-7277HCL | Recombinant Human CRK 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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