Recombinant Human ERCC2 Protein, GST-tagged
Cat.No. : | ERCC2-3457H |
Product Overview : | Human ERCC2 full-length ORF ( AAH08346, 1 a.a. - 405 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 70.29 kDa |
AA Sequence : | MRELKRTLDAKGHGVLEMPSGTGKT VSLLALIMAYQRAYPLEVTKLIYCS RTVPEIEKVIEELRKLLNFYEKQEG EKLPFLGLALSSRKNLCIHPEVTPL RFGKDVDGKCHSLTASYVRAQYQHD TSLPHCRFYEEFDAHGREVPLPAGI YNLDDLKALGRRQGWCPYFLARYSI LHANVVVYSYHYLLDPKIADLVSKE LARKAVVVFDEAHNIDNVCIDSMSV NLTRRTLDRCQGNLETLQKTVLRIK ETDEQRLRDEYRRLVEGLREASAAR ETDAHLANPVLPDEVLQEAVPGSIR TAEHFLGFLRRLLEYVKWRLRVQHV VQESPPAFLSGLAQRVCIQRKPLRF CAERLRSLLHTLEITDLADFSPLTL LANFATLVSTYAKGQAQHCGSSRNQ KRSHP |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ERCC2 excision repair cross-complementing rodent repair deficiency, complementation group 2 [ Homo sapiens ] |
Official Symbol : | ERCC2 |
Synonyms : | ERCC2; excision repair cross-complementing rodent repair deficiency, complementation group 2; xeroderma pigmentosum complementary group D , XPD; TFIIH basal transcription factor complex helicase XPD subunit; EM9; excision repair cross complementing rodent repair deficiency; complementation group 2 protein; MAG; MGC102762; MGC126218; MGC126219; CXPD; BTF2 p80; TFIIH p80; TFIIH 80 kDa subunit; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; basic transcription factor 2 80 kDa subunit; xeroderma pigmentosum complementary group D; xeroderma pigmentosum group D-complementing protein; TFIIH basal transcription factor complex 80 kDa subunit; TFIIH basal transcription factor complex helicase subunit; TTD; XPD; COFS2; |
Gene ID : | 2068 |
mRNA Refseq : | NM_000400 |
Protein Refseq : | NP_000391 |
MIM : | 126340 |
UniProt ID : | P18074 |
Products Types
◆ Recombinant Protein | ||
ERCC2-2842M | Recombinant Mouse ERCC2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ERCC2-11166Z | Recombinant Zebrafish ERCC2 | +Inquiry |
ERCC2-30131TH | Recombinant Human ERCC2, His-tagged | +Inquiry |
ERCC2-2397H | Recombinant Human ERCC2 Protein (Ala404-Leu637), N-His tagged | +Inquiry |
ERCC2-13H | Recombinant Human ERCC2 Protein | +Inquiry |
◆ Lysates | ||
ERCC2-6566HCL | Recombinant Human ERCC2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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