Recombinant Human ERCC2 Protein
Cat.No. : | ERCC2-13H |
Product Overview : | Recombinant Human ERCC2 Protein was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Source : | E. coli |
Species : | Human |
Form : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl. |
Molecular Mass : | ~26.3 kDa |
AA Sequence : | DGIVAFFTSYQYMESTVASWYEQGI LENIQRNKLLFIETQDGAETSVALE KYQEACENGRGAILLSVARGKVSEG IDFVHHYGRAVIMFGVPYVYTQSRI LKARLEYLRDQFQIRENDFLTFDAM RHAAQCVGRAIRGKTDYGLMVFADK RFARGDKRGKLPRWIQEHLTDANLN LTVDEGVQVAKYFLRQMAQPFHRED QLGLSLLSLEQLESEETLKRIEQIA QQL |
Purity : | >90% |
Storage : | Short Term Storage at 4 centigrade, Long Term, please prepare aliquots with 20% glycerol and store at -20 to -80 centigrade. Avoid freeze/thaw cycles. |
Concentration : | 0.12 mg/ml |
Official Full Name : | ERCC excision repair 2, TFIIH core complex helicase subunit |
Gene Name : | ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit [ Homo sapiens (human) ] |
Official Symbol : | ERCC2 |
Synonyms : | EM9; TTD; XPD; TTD1; COFS2; TFIIH |
Gene ID : | 2068 |
mRNA Refseq : | NM_000400 |
Protein Refseq : | NP_000391 |
MIM : | 126340 |
UniProt ID : | P18074 |
Products Types
◆ Recombinant Protein | ||
ERCC2-3457H | Recombinant Human ERCC2 Protein, GST-tagged | +Inquiry |
ERCC2-2842M | Recombinant Mouse ERCC2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ERCC2-11166Z | Recombinant Zebrafish ERCC2 | +Inquiry |
ERCC2-2397H | Recombinant Human ERCC2 Protein (Ala404-Leu637), N-His tagged | +Inquiry |
ERCC2-30131TH | Recombinant Human ERCC2, His-tagged | +Inquiry |
◆ Lysates | ||
ERCC2-6566HCL | Recombinant Human ERCC2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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