Recombinant Human FCER1A Protein (26-205 aa), His-tagged

Cat.No. : FCER1A-2099H
Product Overview : Recombinant Human FCER1A Protein (26-205 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Immunology. Protein Description: Partial.
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Description : Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Source : Yeast
Species : Human
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 23.0 kDa
Protein length : 26-205 aa
AA Sequence : VPQKPKVSLNPPWNRIFKGENVTLT CNGNNFFEVSSTKWFHNGSLSEETN SSLNIVNAKFEDSGEYKCQHQQVNE SEPVYLEVFSDWLLLQASAEVVMEG QPLFLRCHGWRNWDVYKVIYYKDGE ALKYWYENHNISITNATVEDSGTYY CTGKVWQLDYESEPLNITVIKAPRE KYWLQ
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name : FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide [ Homo sapiens ]
Official Symbol : FCER1A
Synonyms : FCER1A; alpha polypeptide; FCE1A; Fc-epsilon RI-alpha; FcERI;
Gene ID : 2205
mRNA Refseq : NM_002001
Protein Refseq : NP_001992
MIM : 147140
UniProt ID : P12319

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Reviews
11/30/2022

    FCER1A can maintain its biological activity and structural integrity under specific experimental conditions.

    11/08/2022

      FCER1A quality is stable and reliable, with no significant differences between batches.

      01/15/2021

        FCER1A has high chemical and physical stability and is suitable for long-term storage and use.

        Q&As (6)

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        Is FCER1A expression regulated? 09/28/2022

        Modulation of FCER1A expression can be achieved through techniques such as gene knockout, gene silencing, or gene transduction. In addition, its expression levels can also be affected by altering environmental factors such as nutrition, inflammation, etc.

        How can I detect the expression level of FCER1A? 07/25/2022

        The expression level of FCER1A can be detected by gene expression profiling or immunohistochemistry.

        Is there a role for FCER1A in the immune system? 11/03/2021

        FCER1A plays a key role in the immune system, recognizing and presenting antigens to T cell receptors, thereby initiating an adaptive immune response.

        What diseases is FCER1A associated with? 09/30/2021

        Studies have shown that FCER1A is associated with the risk of some autoimmune diseases, inflammatory diseases, and certain cancers.

        What is the significance of studying FCER1A? 09/28/2021

        Studying FCER1A can help to gain insight into the mechanisms of immune response and inflammatory response, which is of great significance for the development of new drugs and therapeutic strategies. In addition, it is also of great value for understanding the pathogenesis and prevention of diseases.

        How is FCER1A related to other genes or proteins? 08/20/2021

        FCER1A has complex associations with other genes and proteins, such as its interaction with T cell receptors, inflammatory factors, etc.

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