Recombinant Human FCER1A Protein(Val26-Gln205), His-tagged

Cat.No. : FCER1A-338H
Product Overview : Recombinant Human FCER1A Protein(Val26-Gln205)(P12319-1), fused with C-terminal His Tag, was expressed in HEK293.
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Source : HEK293
Species : Human
Tag : His
Protein length : Val26-Gln205
Form : Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Bio-activity : Immobilized Human Fc epsilon RI alpha, His Tag at 0.2μg/ml (100μl/well) on the plate. Dose response curve for Anti-Fc epsilon RI alpha Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA.
Molecular Mass : The protein has a predicted MW of 22.1 kDa. Due to glycosylation, the protein migrates to 48-65 kDa based on Tris-Bis PAGE result.
Endotoxin : Less than 1EU per ug by the LAL method.
Purity : > 95% as determined by Tris-Bis PAGE
> 95% as determined by HPLC
Storage : -20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3-6 months after reconstitution.
2-8°C for 2-7 days after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Reconstitution : Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Gene Name : FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide [ Homo sapiens ]
Official Symbol : FCER1A
Synonyms : FCER1A; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; FCE1A; high affinity immunoglobulin epsilon receptor subunit alpha; Fc-epsilon RI-alpha; Fc epsilon RI alpha-chain; igE Fc receptor subunit alpha; Fc IgE receptor, alpha polypeptide; high affinity immunoglobulin epsilon receptor alpha-subunit; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; FcERI;
Gene ID : 2205
mRNA Refseq : NM_002001
Protein Refseq : NP_001992
MIM : 147140
UniProt ID : P12319

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Customer Reviews (3)

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Reviews
11/30/2022

    FCER1A can maintain its biological activity and structural integrity under specific experimental conditions.

    11/08/2022

      FCER1A quality is stable and reliable, with no significant differences between batches.

      01/15/2021

        FCER1A has high chemical and physical stability and is suitable for long-term storage and use.

        Q&As (6)

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        Is FCER1A expression regulated? 09/28/2022

        Modulation of FCER1A expression can be achieved through techniques such as gene knockout, gene silencing, or gene transduction. In addition, its expression levels can also be affected by altering environmental factors such as nutrition, inflammation, etc.

        How can I detect the expression level of FCER1A? 07/25/2022

        The expression level of FCER1A can be detected by gene expression profiling or immunohistochemistry.

        Is there a role for FCER1A in the immune system? 11/03/2021

        FCER1A plays a key role in the immune system, recognizing and presenting antigens to T cell receptors, thereby initiating an adaptive immune response.

        What diseases is FCER1A associated with? 09/30/2021

        Studies have shown that FCER1A is associated with the risk of some autoimmune diseases, inflammatory diseases, and certain cancers.

        What is the significance of studying FCER1A? 09/28/2021

        Studying FCER1A can help to gain insight into the mechanisms of immune response and inflammatory response, which is of great significance for the development of new drugs and therapeutic strategies. In addition, it is also of great value for understanding the pathogenesis and prevention of diseases.

        How is FCER1A related to other genes or proteins? 08/20/2021

        FCER1A has complex associations with other genes and proteins, such as its interaction with T cell receptors, inflammatory factors, etc.

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