|Official Full Name||Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide|
|Background||Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.|
|Synonyms||FCER1A; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; FCE1A; high affinity immunoglobulin epsilon receptor subunit alpha; Fc-epsilon RI-alpha; Fc epsilon RI alpha-chain; igE Fc receptor subunit alpha; Fc IgE receptor, alpha polypep|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
FCER1A involved in several pathways and played different roles in them. We selected most pathways FCER1A participated on our site, such as Sphingolipid signaling pathway, Phospholipase D signaling pathway, Fc epsilon RI signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FCER1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Sphingolipid signaling pathway||PLD2; TRAF2; CERS2; NFKB1; TNFRSF1A; RAC2; SPTLC3; PPP2R2C; LASS2; PIK3CG|
|Phospholipase D signaling pathway||PTGFR; Pdgfa&Pdgfb; PIP5K1B; CYTH1; PIK3R5; GRM1; CYTH3; KITLG; RALGDS; INS2|
|Fc epsilon RI signaling pathway||MAPK11; LYN; GRB2; FYN; MAPK8; LCP2; GM-CSF; AKT2; FCER1G; MAPK12|
|Asthma||IL9; CD40; CCL11; RNASE3; HLA-DRB3; HLA-DQA1; HLA-DPB1; HLA-DOB; HLA-DRA; HLA-DQB1|
FCER1A has several biochemical functions, for example, IgE binding, IgE receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FCER1A itself. We selected most functions FCER1A had, and list some proteins which have the same functions with FCER1A. You can find most of the proteins on our site.
|IgE binding||FCER1A; FCER1G; MS4A2; LGALS3; CD247L; Fcer2a; FCER2|
|IgE receptor activity||CD247L; FCER1A; FCER1G; MS4A2|
FCER1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCER1A here. Most of them are supplied by our site. Hope this information will be useful for your research of FCER1A.