Recombinant Human GRK5
Cat.No. : | GRK5-26369TH |
Product Overview : | Recombinant full length GRK5 protein (Human), was expressed by baculovirus in Sf9 insect cells using a N-terminal enzyme tag, MW 95 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). |
Tissue specificity : | Highest levels in heart, placenta, lung >skeletal muscle >brain, liver, pancreas >kidney. |
Biological activity : | Specific Activity: >33 nmol/min/mg. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.Contains 1 AGC-kinase C-terminal domain.Contains 1 protein kinase domain.Contains 1 RGS domain. |
Gene Name : | GRK5 G protein-coupled receptor kinase 5 [ Homo sapiens ] |
Official Symbol : | GRK5 |
Synonyms : | GRK5; G protein-coupled receptor kinase 5; GPRK5; |
Gene ID : | 2869 |
mRNA Refseq : | NM_005308 |
Protein Refseq : | NP_005299 |
MIM : | 600870 |
Uniprot ID : | P34947 |
Chromosome Location : | 10q24-qter |
Pathway : | Alpha-synuclein signaling, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Endocytosis, organism-specific biosystem; |
Function : | ATP binding; G-protein coupled receptor kinase activity; nucleotide binding; phospholipid binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
GRK5-760H | Recombinant Human GRK5 protein(Met1-Ser590), His-tagged | +Inquiry |
GRK5-5356H | Recombinant Human GRK5 Protein, GST-tagged | +Inquiry |
GRK5-2366R | Recombinant Rat GRK5 Protein, His (Fc)-Avi-tagged | +Inquiry |
Grk5-1051M | Recombinant Mouse Grk5 Protein, MYC/DDK-tagged | +Inquiry |
GRK5-2359H | Recombinant Human GRK5 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
GRK5-640HCL | Recombinant Human GRK5 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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