| Description : |
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family. Mutations in this gene are associated with Immunodeficiency 45. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
25.6 kDa |
| Protein Length : |
515 |
| AA Sequence : |
MLLSQNAFIFRSLNLVLMVYISLVF GISYDSPDYTDESCTFKISLRNFRS ILSWELKNHSIVPTHYTLLYTIMSK PEDLKVVKNCANTTRSFCDLTDEWR STHEAYVTVLEGFSGNTTLFSCSHN FWLAIDMSFEPPEFEIVGFTNHINV MVKFPSIVEEELQFDLSLVIEEQSE GIVKKHKPEIKGNMSGNFTYIIDKL IPNTNYCVSVYLEHSDEQAVIKSPL KCTLLPPGQESESAESAKIGGIITV FLIALVLTSTIVTLKWIGYICLRNS LPKVLNFHNFLAWPFPNLPPLEAMD MVEVIYINRKKKVWDYNYDDESDSD TEAAPRTSGGGYTMHGLTVRPLGQA SATSTESQLIDPESEEEPDLPEVDV ELPTMPKDSPQQLELLSGPCERRKS PLQDPFPEEDYSSTEGSGGRITFNV DLNSVFLRVLDDEDSDDLEAPLMLS SHLEEMVDPEDPDNVQSNHLLASGE GTQPTFPSPSSEGLWSEDAPSDQSD TSESDVDLGDGYIMR |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
