Recombinant Human IL12A, His-tagged IL12A-42H

Recombinant Human IL12A, His-tagged


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Recombinant Human IL12A, His-tagged

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Cat.No. : IL12A-42H Optional Service: Optional requirements on this protein
Product Overview : Recombinant Human Interleukin-10 produced inE.Coliis single, a non-glycosylated, Polypeptide chain containing 160 amino acids fragment (19-178) and having a total molecular mass of 18.6 kDa with an amino-terminal His-tagged. The IL-10 His-Tag is purified by proprietary chromatographic techniques.
Description : Interleukin-10 is a multifunctional cytokine produced by a variety of cell types including T helper cells activated B cells and activated macrophages. Interleukin-10 regulates immune-mediated inflammation and modulates the function of cells such as lymphocytes, monocytes, natural killer cells and dendritic cells.
Source : Escherichia Coli.
Physical Appearance : Sterile Filtered clear solution (0.083mg/1ml)
Purity : Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation : Interleukin-12 p35 His-Tag is supplied in 20mM Tris HCL pH=8, 0.5 mM DTT and 50% glycerol.
Storage : Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
PDB rendering based on 1f45 :

Gene Name : IL12A interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) [ Homo sapiens ]
Synonyms : NKSF1; CTL maturation factor (TCMF); Cytotoxic lymphocyte maturation factor 35 kDa subunit (CLMF p35); TSF; Edodekin-alpha; IL-12 p35; SGT2; FLJ39002; CLMF; IL-12A; NFSK; P35; Cytotoxic lymphocyte maturation factor 35 kDa subunit; IL-12 subunit p35; IL-12, subunit p35; NF cell stimulatory factor chain 1; cytotoxic lymphocyte maturation factor 1, p35; interleukin 12, p35; interleukin 12A; interleukin 12A (natural killer cell stimulatory factor 1,cytotoxic lymphocytematuration factor 1, p35); interleukin-12 alpha chain; natural killer cell stimulatory factor 1, 35 kD subunit 2; IL12A.
Gene ID : 3592
mRNA Refseq : NM_000882
Protein Refseq : NP_000873
MIM : 161560
UniProt ID : P29459
Chromosome Location : 3q25.33-q26
Pathway : Allograft rejection; Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway; Type I diabetes mellitus
Function : contributes_to cytokine activity; contributes_to growth factor activity; interleukin-12 beta subunit binding; interleukin-12 receptor binding; interleukin-27 binding; protein binding; protein heterodimerization activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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