Recombinant Human IL1R2 Protein (ECD), Fc-His-tagged(C-ter) IL1R2-165H

Recombinant Human IL1R2 Protein (ECD), Fc-His-tagged(C-ter)

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Recombinant Human IL1R2 Protein (ECD), Fc-His-tagged(C-ter)

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Cat.No. : IL1R2-165H Optional Service: Optional requirements on this protein
Product Overview : Recombinant Human IL1R2 Protein (ECD) with Fc-His tag (C-ter) was expressed in HEK293.
Description : The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]
Source : HEK293
Species : Human
Tag : Fc-His(C-ter)
Form : Powder
Protein Length : Met1-Glu343
Endotoxin : Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test.
Purity : > 97% (by SDS-PAGE)
Applications : Binding, SDS-PAGE
Notes : For laboratory research only, not for drug, diagnostic or other use.
Storage : Lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
Storage Buffer : PBS (pH 7.4)
Reconstitution : Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water.
SDS-PAGE :

Gene Name : IL1R2 interleukin 1 receptor, type II [ Homo sapiens ]
Official Symbol : IL1R2
Synonyms : IL1R2; interleukin 1 receptor, type II; IL1RB; interleukin-1 receptor type 2; CD121b; CDw121b; IL-1R-2; IL-1RT2; IL-1RT-2; IL-1R-beta; antigen CDw121b; IL-1 type II receptor; interleukin-1 receptor beta; interleukin-1 receptor type II; CD121 antigen-like family member B; type II interleukin-1 receptor, beta; MGC47725;
Gene ID : 7850
mRNA Refseq : NM_004633
Protein Refseq : NP_004624
MIM : 147811
UniProt ID : P27930
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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