Recombinant Human IL28RA Protein, GST-tagged

• Cat.No.: IL28RA-5201H
• Product Overview: Human IL28RA partial ORF ( NP_734464, 51 a.a. - 150 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 36.74 kDa
• AA Sequence: QDVTYFVAYQSSPTRRRWREVEECA GTKELLCSMMCLKKQDLYNKFKGRV RTVSPSSKSPWVESEYLDYLFEVEP APPVLVLTQTEEILSANATYQLPPC
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: IL28RA interleukin 28 receptor, alpha (interferon, lambda receptor) [ Homo sapiens ]
• Official Symbol: IL28RA
• Synonyms: IL28RA; interleukin 28 receptor, alpha (interferon, lambda receptor); interleukin 28 receptor, alpha; interleukin-28 receptor subunit alpha; CRF2/12; IFNLR; IL 28R1; interferon lambda receptor 1; CRF2-12; IL-28RA; IL-28R-alpha; IFN-lambda-R1; IFN-lambda receptor 1; interleukin 28 receptor A; IL-28 receptor subunit alpha; interferon lambda, receptor 1; interleukin 28 alpha receptor; class II cytokine receptor CRF2/12; interleukin or cytokine receptor 2; cytokine receptor class-II member 12; cytokine receptor family 2 member 12; likely interleukin or cytokine receptor 2; LICR2; IFNLR1; IL-28R1
• Gene ID: 163702
• mRNA Refseq: NM_170743
• Protein Refseq: NP_734464
• MIM: 607404
• UniProt ID: Q8IU57

Reviews

10/04/2020

Small harm to the human body, high safety.

08/08/2020

The detection method is very sensitive and can be detected in small quantities.

01/14/2019

It is very stable and does not denature even at low temperatures.

Q&As

Which types of hepatitis B can IL-28RA be treated?

IL-28RA can treat hepatitis B virus infection and is also used in the development of chronic hepatitis B.

What is the action mechanism of IL-28RA in vivo?

IL-28RA can enhance the body's immune function, thereby inhibiting the growth and reproduction of pathogens.

Does IL-28RA have an effect on human body?

At normal doses, IL-28RA has no significant adverse effects on humans.

IL-28ra in a role in the treatment of hepatitis b is what?

Recombinant IL-28RA can effectively treat hepatitis B without causing significant side effects.

Is IL-28RA suitable for clinical treatment?

IL-28RA is suitable for clinical use and has been used in many medical facilities.

Can IL-28RA improve the body's resistance to disease?

This protein can improve the body's resistance to disease.