Active Recombinant Human IL5 Protein (116 aa)
Cat.No. : | IL5-354I |
Product Overview : | Recombinant Human Interleukin-5 (rhIL-5) produced in E. coli is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 116 amino acids each. A fully biologically active molecule, rhIL-5 has a molecular mass of 26.5 kDa analyzed by non-reducing SDS-PAGE and is obtained by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release. |
Source : | E. coli |
Species : | Human |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | ED50 < 1.0 ng/mL, measured by a cell proliferation assay using TF-1 Cells, corresponding to a specific activity of > 1.0 × 10^6 units/mg. |
Molecular Mass : | 26.5 kDa, observed by non-reducing SDS-PAGE. |
Protein Length : | 116 |
AA Sequence : | MIPTEIPTSALVKETLALLSTHRTL LIANETLRIPVPVHKNHQLCTEEIF QGIGTLESQTVQGGTVERLFKNLSL IKKYIDGQKKKCGEERRRVNQFLDY LQEFLGVMNTEWIIES |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 95% by SDS-PAGE. |
Storage : | Lyophilized recombinant Human Interleukin-5 (rhIL-5) remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, rhIL-5 should be stable up to 2 weeks at 4 centigrade or up to 3 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against 25mM Tris, pH8.0. |
Reconstitution : | Reconstituted in ddH2O at 100 μg/mL. |
Gene Name : | IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Homo sapiens ] |
Official Symbol : | IL5 |
Synonyms : | IL5; interleukin 5 (colony-stimulating factor, eosinophil); interleukin-5; B cell differentiation factor I; EDF; eosinophil differentiation factor; IL 5; interleukin 5; T cell replacing factor; TRF; T-cell replacing factor; B-cell differentiation factor I; IL-5; |
Gene ID : | 3567 |
mRNA Refseq : | NM_000879 |
Protein Refseq : | NP_000870 |
MIM : | 147850 |
UniProt ID : | P05113 |
Products Types
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◆ Lysates | ||
IL5-456CCL | Recombinant Canine IL5 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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