Recombinant Human Interleukin 28 Receptor, Alpha (interferon, lambda receptor) IL28RA-601H

Recombinant Human Interleukin 28 Receptor, Alpha (interferon, lambda receptor)

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Cat.No. : IL28RA-601H Optional Service: Optional requirements on this protein
Product Overview : Recombinant HumanIFN-lambda 2 contains 175 amino acid residues.
Description : IL28RA is a subunitfor the interleukin-28 receptor. IL28RA is its human gene. The proteinencoded by this gene belongs to the class II cytokine receptor family. Thisprotein forms a receptor complex with interleukine 10 receptor, beta(IL10RB). The receptor complex has been shown to interact with three closelyrelated cytokines, including interleukin 28A (IL28A), interleukin 28B(IL28B), and interleukin 29 (IL29). The expression of all three cytokines canbe induced by viral infection.
Source : E. coli
Species : Human
Form : Lyophilized withoutadditives
Purity : > 95% asdetermined by SDS-PAGE and HPLC analysis.
Molecular Weight : 19.8 kDa
Endotoxin Level : < 0.1 ng/μg ofIFN-lambda 2
Biological Activity : Determined by itsability to activate STAT following receptor-ligand interaction.
Reconstitution : Centrifuge vialprior to opening. First add sterile distilled water to the vial to fullysolubilize the protein to a concentration of 0.1-1.0 mg/ml. After completesolubilization of the protein, it can be further diluted to other aqueoussolutions.
Storage : Store lyophilizedprotein at -20°C and reconstituted protein in working aliquots at -20°C.Avoid repeated freeze-thaw cycles.
OfficialSymbol : IL28RA
Pathways : Cytokine-cytokinereceptor interaction; Jak-STAT signaling pathway
Rendering based onPDB 3OG4. :

Gene Name : IL28RA interleukin 28receptor, alpha (interferon, lambda receptor) [ Homo sapiens ]
Synonyms : IL28RA; interleukin28 receptor, alpha (interferon, lambda receptor); IFNLR; LICR2; IFNLR1;CRF2/12; IL-28R1; interleukin-28 receptor subunit alpha; CRF2-12;IL-28RA; IL-28R-alpha; IFN-lambda-R1; OTTHUMP00000003067; OTTHUMP00000003068;OTTHUMP00000003069; OTTHUMP00000003070; IFN-lambda receptor 1; interleukin 28receptor A; IL-28 receptor subunit alpha; interferon lambda receptor 1;interferon lambda, receptor 1; class II cytokine receptor CRF2/12;interleukin or cytokine receptor 2; cytokine receptor class-II member 12;cytokine receptor family 2 member 12; likely interleukin or cytokine receptor2; Interleukin-28receptor subunit alpha; Cytokinereceptor class-II member 12; Cytokine receptor family 2 member 12; Interferonlambda receptor 1; Likely interleukin or cytokine receptor 2
Gene ID : 163702
mRNA Refseq : NM_170743
Protein Refseq : NP_734464
MIM : 607404
UniProt ID : Q8IU57
Chromosome Location : 1p36.11
Function : contributes tocytokine receptor activity; protein binding; receptor activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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