| Cat.No. : |
IL28RA-601H
Optional Service: Optional requirements on this protein
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| Product Overview : |
Recombinant HumanIFN-lambda 2 contains 175 amino acid residues. |
| Description : |
IL28RA is a subunitfor the interleukin-28 receptor. IL28RA is its human gene. The proteinencoded by this gene belongs to the class II cytokine receptor family. Thisprotein forms a receptor complex with interleukine 10 receptor, beta(IL10RB). The receptor complex has been shown to interact with three closelyrelated cytokines, including interleukin 28A (IL28A), interleukin 28B(IL28B), and interleukin 29 (IL29). The expression of all three cytokines canbe induced by viral infection. |
| Source : |
E. coli |
| Species : |
Human |
| Form : |
Lyophilized withoutadditives |
| Purity : |
> 95% asdetermined by SDS-PAGE and HPLC analysis. |
| Molecular Weight : |
19.8 kDa |
| Endotoxin Level : |
< 0.1 ng/μg ofIFN-lambda 2 |
| Biological Activity : |
Determined by itsability to activate STAT following receptor-ligand interaction. |
| Reconstitution : |
Centrifuge vialprior to opening. First add sterile distilled water to the vial to fullysolubilize the protein to a concentration of 0.1-1.0 mg/ml. After completesolubilization of the protein, it can be further diluted to other aqueoussolutions. |
| Storage : |
Store lyophilizedprotein at -20°C and reconstituted protein in working aliquots at -20°C.Avoid repeated freeze-thaw cycles. |
| OfficialSymbol : |
IL28RA |
| Pathways : |
Cytokine-cytokinereceptor interaction; Jak-STAT signaling pathway |
| Rendering based onPDB 3OG4. : |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
