Recombinant Human Interleukin-4, His Tag
Cat.No. : | IL4-409H |
Product Overview : | Interleukin-4 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 150 amino acids fragment (25-153) and having a total molecular mass of 19.62kDa with an amino-terminal hexahistidine tag. The IL-4 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
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Cat. No. : | IL4-409H |
Description : | Interleukin-4 is a pleiotropic cytokine produced primarily by activated T lymphocytes, basophils and mast cells. Multiple immune response-modulating functions are performed by IL-4 on a variety of cell types and it has an important role in the regulator of isotype switching, induction of IgE production in B lymphocytes and differentiation of precursor T helper cells. IL-4 binds to both membrane-bound and secreted soluble IL-4 receptors. |
Source : | Human |
Host : | Escherichia Coli. |
Form : | Interleukin-4 His-Tag is supplied in 1x PBS, 50% glycerol. |
Purity : | Greater than 95.0% as determined by SDS-PAGE. |
Physical Appearance : | Sterile Filtered clear solution. |
Amino acid sequence : | MGSSHHHHHH SSGLVPRGSH MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS. |
Storage : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
Gene Name : | IL4 interleukin 4 [ Homo sapiens ] |
Official Symbol : | IL4 |
Synonyms : | interleukin-4; binetrakin; pitrakinra; OTTHUMP00000066049; OTTHUMP00000066050; B cell growth factor 1; B_cell stimulatory factor 1; lymphocyte stimulatory factor 1 |
Gene ID : | 3565 |
mRNA Refseq : | NM_000589 |
Protein Refseq : | NP_000580 |
UniProt ID : | P05112 |
Chromosome Location : | 5q31.1 |
Pathway : | Allograft rejection; CD40/CD40L signaling; Fc epsilon RI signaling pathway; Hematopoietic cell lineage; Jak-STAT signaling pathway |
Function : | cytokine activity; growth factor activity; interleukin-4 receptor binding; protein binding |
Products Types
◆ Recombinant Protein | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Ask a questionCustomer Reviews (3)
Write a reviewBy testing immunogenicity in animal models, detect whether an immune response is induced.
The structure of the recombinant protein was analyzed by nuclear magnetic resonance (NMR), X-ray crystallography or electron microscopy, and the results showed that the protein was stable.
This protein has good stability, and the test results of heat resistance, acid and alkali resistance and protease degradation resistance are good.
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