Recombinant Human S100A12, GST-tagged
Cat.No. : | S100A12-2483H |
Product Overview : | Recombinant Human S100A12 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
Availability | February 13, 2025 |
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Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-92aa |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | S100A12 S100 calcium binding protein A12 [ Homo sapiens ] |
Official Symbol : | S100A12 |
Synonyms : | S100A12; S100 calcium binding protein A12; S100 calcium binding protein A12 (calgranulin C) , S100 calcium binding protein A12 (calgranulin C); protein S100-A12; CAAF1; CAGC; CGRP; ENRAGE; MRP6; p6; EN-RAGE; calgranulin C; calgranulin-C; neutrophil S100 protein; calcium-binding protein in amniotic fluid 1; S100 calcium-binding protein A12 (calgranulin C); extracellular newly identified RAGE-binding protein; |
Gene ID : | 6283 |
mRNA Refseq : | NM_005621 |
Protein Refseq : | NP_005612 |
MIM : | 603112 |
UniProt ID : | P80511 |
Chromosome Location : | 1q21 |
Pathway : | Activated TLR4 signalling, organism-specific biosystem; Advanced glycosylation endproduct receptor signaling, organism-specific biosystem; Cytosolic sensors of pathogen-associated DNA, organism-specific biosystem; DAI mediated induction of type I IFNs, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88 cascade initiated on plasma membrane, organism-specific biosystem; |
Function : | RAGE receptor binding; RAGE receptor binding; calcium ion binding; protein binding; zinc ion binding; |
Products Types
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S100A12-1936H | Recombinant Human S100A12 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100A12-33H | Recombinant Human S100A12 protein, Myc/DDK-tagged | +Inquiry |
S100A12-2002H | Recombinant Human S100A12 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
S100A12-2094HCL | Recombinant Human S100A12 293 Cell Lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewPrecise protein quantification, fundamental for data accuracy in our experiments.
Timely antibody validation, a valuable asset for our laboratory.
Exceptional protein expression optimization support, greatly enhances our research.
Q&As (7)
Ask a questionS100A12 regulates the production of pro-inflammatory cytokines, impacting the extent and severity of inflammation.
S100A12 is implicated in inflammatory diseases like rheumatoid arthritis, contributing to joint inflammation and damage.
S100A12 contributes to vascular inflammation, potentially leading to the development of atherosclerosis.
S100A12 plays a role in the innate immune response against bacterial infections, enhancing pathogen detection and response.
Changes in S100A12 expression can exacerbate chronic inflammatory and autoimmune diseases, affecting disease progression and symptoms.
S100A12 influences calcium signaling in immune cells, affecting their activation and function.
S100A12 binds to receptors on immune cells, triggering inflammatory responses and modulating immune activity.
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