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Recombinant Human S100A12 protein, GST-tagged

Cat.No. : S100A12-3460H
Product Overview : Recombinant Human S100A12 protein(P80511)(2-92aa), fused to N-terminal GST tag, was expressed in E. coli.
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Source : E. coli
Species : Human
Tag : GST
Form : If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Molecular Mass : 37.4 kDa
Protein length : 2-92aa
AA Sequence : TKLEEHLEGIVNIFHQYSVRKGHFD TLSKGELKQLLTKELANTIKNIKDK AVIDEIFQGLDANQDEQVDFQEFIS LVAIALKAAHYHTHKE
Purity : Greater than 90% as determined by SDS-PAGE.
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Reconstitution : Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%.
Gene Name : S100A12 S100 calcium binding protein A12 [ Homo sapiens ]
Official Symbol : S100A12
Synonyms : S100A12; S100 calcium binding protein A12; S100 calcium binding protein A12 (calgranulin C) , S100 calcium binding protein A12 (calgranulin C); protein S100-A12; CAAF1; CAGC; CGRP; ENRAGE; MRP6; p6; EN-RAGE; calgranulin C; calgranulin-C; neutrophil S100 protein; calcium-binding protein in amniotic fluid 1; S100 calcium-binding protein A12 (calgranulin C); extracellular newly identified RAGE-binding protein;
Gene ID : 6283
mRNA Refseq : NM_005621
Protein Refseq : NP_005612
MIM : 603112
UniProt ID : P80511

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
09/30/2022

    Precise protein quantification, fundamental for data accuracy in our experiments.

    03/11/2020

      Timely antibody validation, a valuable asset for our laboratory.

      02/26/2019

        Exceptional protein expression optimization support, greatly enhances our research.

        Q&As (7)

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        What are the mechanisms by which S100A12 modulates the expression of pro-inflammatory cytokines? 11/30/2022

        S100A12 regulates the production of pro-inflammatory cytokines, impacting the extent and severity of inflammation.

        What role does S100A12 play in the pathogenesis of inflammatory diseases like rheumatoid arthritis? 03/16/2022

        S100A12 is implicated in inflammatory diseases like rheumatoid arthritis, contributing to joint inflammation and damage.

        What is the impact of S100A12 on vascular inflammation and the development of atherosclerosis? 02/23/2022

        S100A12 contributes to vascular inflammation, potentially leading to the development of atherosclerosis.

        How does S100A12 contribute to the innate immune response, particularly in bacterial infections? 04/25/2021

        S100A12 plays a role in the innate immune response against bacterial infections, enhancing pathogen detection and response.

        How do alterations in S100A12 expression or function affect chronic inflammatory conditions and autoimmune diseases? 06/20/2020

        Changes in S100A12 expression can exacerbate chronic inflammatory and autoimmune diseases, affecting disease progression and symptoms.

        How does S100A12 influence calcium signaling and cellular activation in immune cells? 02/20/2020

        S100A12 influences calcium signaling in immune cells, affecting their activation and function.

        How does S100A12 (S100 Calcium Binding Protein A12) interact with receptors on immune cells to modulate inflammation? 01/10/2018

        S100A12 binds to receptors on immune cells, triggering inflammatory responses and modulating immune activity.

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