Recombinant Human S100A12, His-tagged
Cat.No. : | S100A12-30229TH |
Product Overview : | Recombinant full length Human S100A12 with an N terminal His tag; 101 amino acids with tag, predicted MWt: 11.6 kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21.This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. |
Protein length : | 91 amino acids |
Conjugation : | HIS |
Molecular Weight : | 11.600kDa inclusive of tags |
Source : | E. coli |
Tissue specificity : | Monocytes and lymphocytes. |
Form : | Lyophilised:Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Filter the product by an appropriate sterile filter before using it in the cell culture. |
Purity : | by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 50mM Sodium chloride, 20mM Tris, pH 7.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MKHHHHHHAS TKLEEHLEGI VNIFHQYSVR KGHFDTLSKG ELKQLLTKEL ANTIKNIKDK AVIDEIFQGL DANQDEQVDFQEFISLVAIA LKAAHYHTHK E |
Sequence Similarities : | Belongs to the S-101 family.Contains 2 EF-hand domains. |
Gene Name : | S100A12 S100 calcium binding protein A12 [ Homo sapiens ] |
Official Symbol : | S100A12 |
Synonyms : | S100A12; S100 calcium binding protein A12; S100 calcium binding protein A12 (calgranulin C) , S100 calcium binding protein A12 (calgranulin C); protein S100-A12; CAAF1; CAGC; CGRP; ENRAGE; MRP6; p6; |
Gene ID : | 6283 |
mRNA Refseq : | NM_005621 |
Protein Refseq : | NP_005612 |
MIM : | 603112 |
Uniprot ID : | P80511 |
Chromosome Location : | 1q21 |
Pathway : | Activated TLR4 signalling, organism-specific biosystem; Advanced glycosylation endproduct receptor signaling, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88 cascade initiated on plasma membrane, organism-specific biosystem; |
Function : | RAGE receptor binding; RAGE receptor binding; calcium ion binding; protein binding; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
S100A12-063H | Recombinant Human S100A12 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
S100A12-1936H | Recombinant Human S100A12 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100A12-33H | Recombinant Human S100A12 protein, Myc/DDK-tagged | +Inquiry |
S100A12-3096H | Active Recombinant Human S100A12 protein(Met1-Glu92) | +Inquiry |
S100A12-289H | Recombinant Human S100A12 Protein, His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
S100A12-2094HCL | Recombinant Human S100A12 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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