Recombinant Human S100A12 Protein, MYC/DDK-tagged, C13 and N15-labeled
Cat.No. : | S100A12-063H |
Product Overview : | S100A12 MS Standard C13 and N15-labeled recombinant protein (NP_005612) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc&DDK |
Molecular Mass : | 10.6 kDa |
AA Sequence : | MTKLEEHLEGIVNIFHQYSVRKGHF DTLSKGELKQLLTKELANTIKNIKD KAVIDEIFQGLDANQDEQVDFQEFI SLVAIALKAAHYHTHKETRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | S100A12 S100 calcium binding protein A12 [ Homo sapiens (human) ] |
Official Symbol : | S100A12 |
Synonyms : | S100A12; S100 calcium binding protein A12; CAAF1; CAGC; CGRP; ENRAGE; MRP-6; MRP6; p6; protein S100-A12; EN-RAGE; calcitermin; calcium-binding protein in amniotic fluid 1; calgranulin C; extracellular newly identified RAGE-binding protein; migration inhibitory factor-related protein 6; neutrophil S100 protein |
Gene ID : | 6283 |
mRNA Refseq : | NM_005621 |
Protein Refseq : | NP_005612 |
MIM : | 603112 |
UniProt ID : | P80511 |
Products Types
◆ Recombinant Protein | ||
S100A12-1936H | Recombinant Human S100A12 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100A12-33H | Recombinant Human S100A12 protein, Myc/DDK-tagged | +Inquiry |
S100A12-3096H | Active Recombinant Human S100A12 protein(Met1-Glu92) | +Inquiry |
S100A12-2002H | Recombinant Human S100A12 Protein, His-tagged | +Inquiry |
S100A12-289H | Recombinant Human S100A12 Protein, His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
S100A12-2094HCL | Recombinant Human S100A12 293 Cell Lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewPrecise protein quantification, fundamental for data accuracy in our experiments.
Timely antibody validation, a valuable asset for our laboratory.
Exceptional protein expression optimization support, greatly enhances our research.
Q&As (7)
Ask a questionS100A12 regulates the production of pro-inflammatory cytokines, impacting the extent and severity of inflammation.
S100A12 is implicated in inflammatory diseases like rheumatoid arthritis, contributing to joint inflammation and damage.
S100A12 contributes to vascular inflammation, potentially leading to the development of atherosclerosis.
S100A12 plays a role in the innate immune response against bacterial infections, enhancing pathogen detection and response.
Changes in S100A12 expression can exacerbate chronic inflammatory and autoimmune diseases, affecting disease progression and symptoms.
S100A12 influences calcium signaling in immune cells, affecting their activation and function.
S100A12 binds to receptors on immune cells, triggering inflammatory responses and modulating immune activity.
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