Species : |
Human |
Source : |
Human Cells |
Tag : |
His |
Description : |
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. |
Form : |
Purified protein formulated in a sterile solution of TBS buffer, pH7.288, without any preservatives. |
Molecular Mass : |
20.39kD |
Endotoxin : |
Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
Purity : |
>90% by SDS-PAGE gel and Coomassie Blue staining |
Applications : |
Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies. |