SDC1

  • Official Full Name

    syndecan 1

  • Overview

    CD138/Syndecan-1 is a transmembrane heparin sulphate proteoglycan which is made up of one core protein and five glycosaminoglycan. CD138 is expected to play a role in cell adhesion. It is expressed on the surface of pre-B cells and plasma cells but is absent from mature B cells. It is lost from the apoptotic myeloma cells.
  • Synonyms

    SDC1; syndecan 1; syndecan-1; synstatin; Sstn; Synd; CD138; Synd1; syn-1; AA408134; AA409076;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • GMP Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cattle
  • Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
  • Cynomolgus
  • Homo sapiens (Human)
  • Human
  • Mesocricetus auratus (Golden hamster)
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293F
  • Human Cell
  • Human Cells
  • Mammalian Cell
  • Mammalian cells
  • Mammalian Cells
  • Yeast
  • C
  • hFc
  • 6×His
  • His
  • Fc
  • Avi
  • His (Fc)
  • GST
  • His|GST
  • His|T7
  • SUMO
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SDC1-523H Active Recombinant Human SDC1 Protein, His-tagged Mammalian cells His Gln18-Glu251
Human SDC1-31494TH Recombinant Human SDC1 E.coli N/A
Human SDC1-2033H Recombinant Human SDC1 protein, His & GST-tagged E.coli His/GST Gln23~Leu253 (Accession # P18827)
Human SDC1-2390H Recombinant Human Syndecan 1 E.coli N/A
Human SDC1-3352H Recombinant Human SDC1, His tagged Human Cell His
Human SDC1-29H Recombinant Human SDC1 Protein, His-tagged E.coli His Gln23~Leu253
Human SDC1-188H Recombinant Human SDC1 Protein, His-tagged HEK293 His
Human SDC1-2253HCL Recombinant Human SDC1 cell lysate Human Cell N/A
Human SDC1-327H Recombinant Human SDC1 Protein (Gln 23 - Gly 254), His-tagged HEK293 His Gln 23 - Gly 254
Human SDC1-187HG Active GMP Recombinant Human SDC1 protein, Fc-tagged HEK293 Fc DNA sequence encoding Human CD138(UniProtKB/Swiss-Prot: P18827.3) was expressed with Fc tag at the C-terminal.
Human SDC1-15H Recombinant Human SDC1 Protein, His-tagged E.coli His
Human SDC1-1845H Active Recombinant Human SDC1 protein, His & Avi-tagged, Biotinylated HEK293 His & Avi Gln 23 - Gly 254
Human SDC1-4032H Recombinant Human SDC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SDC1-3474H Recombinant Human SDC1 protein, His-SUMO-tagged E.coli His-SUMO 23-254aa
Human SDC1-953H Recombinant Human SDC1 Protein, His-tagged Human Cells His
Human SDC1-452H Recombinant Human SDC1 Protein, His-tagged HEK293 His 310
Human SDC1-4032H-B Recombinant Human SDC1 Protein Pre-coupled Magnetic Beads HEK293
Human SDC1-1218H Recombinant Human SDC1 Protein, His-tagged HEK293F N-His Gln23-Leu253
Human SDC1-1296H Active Recombinant Human SDC1 protein, Fc-tagged HEK293 Fc Gln 23 - Gly 254
Human SDC1-5080H Recombinant Human SDC1 Protein (Met1-Glu136), C-His tagged Mammalian cells C-His Met1-Glu136
Human SDC1-557H Recombinant Human SDC1 Protein (Gln23-Gly254), C-hFc and 6×His-tagged HEK293 C-hFc and 6×His Gln23-Gly254
Human SDC1-126H Recombinant Human SDC1 Protein, C-His-tagged E.coli C-His
Human SDC1-0694H Active Recombinant Human SDC1 protein, His-tagged, FITC-Labeled HEK293 His Gln23-Gly254
Human SDC1-0903H Recombinant Human SDC1 Protein (Gln23-Gly254), N-GST tagged E.coli N-GST Gln23-Gly254
Human SDC1-5079H Recombinant Human SDC1 Protein (Met1-Glu251), C-His tagged Mammalian cells C-His Met1-Glu251
Human SDC1-0695H Active Recombinant Human SDC1 protein, Fc-Avi-tagged, Biotinylated HEK293 Fc-Avi Gln23-Gly254
Human SDC1-6248H Recombinant Human SDC1 Protein (Gln23-Glu251), C-His tagged Mammalian cells C-His Gln23-Glu251
Mouse Sdc1-2034M Recombinant Mouse Sdc1 protein, His & GST-tagged E.coli His/GST Gln23~Gly255 (Accession # P18828)
Mouse Sdc1-4065M Recombinant Mouse Sdc1 protein(Met1-Glu252), His-tagged HEK293 C-His Met1-Glu252
Mouse SDC1-2089MCL Recombinant Mouse SDC1 cell lysate Human Cell N/A
Mouse Sdc1-7958M-B Recombinant Mouse Sdc1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Sdc1-7958M Recombinant Mouse Sdc1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Sdc1-278M Recombinant Mouse Sdc1 Protein, His-tagged Mammalian Cells His
Rat Sdc1-8784R Recombinant Rat Sdc1 protein(Met1-Lys253), hFc-tagged HEK293 C-hFc Met1-Lys253
Rat Sdc1-2035R Recombinant Rat Sdc1 protein, His & GST-tagged E.coli His/GST Ser58~Ala313 (Accession # P26260)
Rat SDC1-5284R Recombinant Rat SDC1 Protein Mammalian Cell His
Rat Sdc1-8785R Recombinant Rat Sdc1, His tagged HEK293 His Met1-Lys253
Rat SDC1-1295RCL Recombinant Rat SDC1 cell lysate Human Cell N/A
Rat Sdc1-8784RA Recombinant Rat Sdc1 protein, Fc-tagged, APC labeled HEK293 Fc
Rat Sdc1-8784RAF488 Recombinant Rat Sdc1 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 472
Rat Sdc1-8784RAF555 Recombinant Rat Sdc1 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 472
Rat Sdc1-8784RAF647 Recombinant Rat Sdc1 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 472
Rat SDC1-4943R Recombinant Rat SDC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Sdc1-8784RF Recombinant Rat Sdc1 Protein, Fc-tagged, FITC conjugated HEK293 Fc 472
Rat Sdc1-2047R Recombinant Rat Sdc1 Protein, His-tagged E.coli N-His Gln23-Gly257
Rat Sdc1-8784RP Recombinant Rat Sdc1 protein, Fc-tagged, R-PE labeled HEK293 Fc
Rat Sdc1-3475R Recombinant Rat Sdc1 protein, His-GST-tagged E.coli His/GST 23-257aa
Rat SDC1-4943R-B Recombinant Rat SDC1 Protein Pre-coupled Magnetic Beads HEK293
Rat Sdc1-5512R Recombinant Rat Sdc1 protein, His-tagged Yeast His 23-257aa
Cattle SDC1-2032C Recombinant Cattle SDC1 protein, His & T7-tagged E.coli His/T7 Ser47~Lys305 (Accession # Q08DZ5)
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) RFL23238CF Recombinant Full Length Cricetulus Griseus Syndecan-1(Sdc1) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (23-309)
Cynomolgus SDC1-15C Recombinant Cynomolgus SDC1 Protein, hFc-tagged HEK293 hFc Met1-Glu251
Homo sapiens (Human) RFL36021HF Recombinant Full Length Human Syndecan-1(Sdc1) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (23-310)
Mesocricetus auratus (Golden hamster) RFL199MF Recombinant Full Length Mesocricetus Auratus Syndecan-1(Sdc1) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (23-309)
Mus musculus (Mouse) RFL19885MF Recombinant Full Length Mouse Syndecan-1(Sdc1) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (23-311)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

SDC1 involved in several pathways and played different roles in them. We selected most pathways SDC1 participated on our site, such as ECM-receptor interaction, Cell adhesion molecules (CAMs), Malaria, which may be useful for your reference. Also, other proteins which involved in the same pathway with SDC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ECM-receptor interactionCD36;DAG1;ITGA1;COL27A1;GP6;ITGA7;COL11A2;COL3A1;COL2A1A
Cell adhesion molecules (CAMs)NRXN1A;JAM3B;CNTNAP1;CD28;HLA-DQB1;NLGN2B;NLGN3A;CLDNB;CADM3
MalariaKLRK1;IL6;MET;THBS3;HGF;HBA1;HBA2;TLR4;VCAM1
Proteoglycans in cancerCAV3;PTCH1;GPC1;LUM;IGF1R;PIK3R1;TGFB1;GAB1;FZD2

SDC1 has several biochemical functions, for example, glycoprotein binding, protein C-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SDC1 itself. We selected most functions SDC1 had, and list some proteins which have the same functions with SDC1. You can find most of the proteins on our site.

Function Related Protein
glycoprotein bindingBBC3;IGF2R;PTBP3;DNAJC5;EDEM2;FOXRED2;TGFB1;SELP;TFRC
protein C-terminus bindingMSH2;ERCC6;CD2AP;XRCC4;HSPG2;YAP1;RAD51;DLG4;FIGN
protein bindingRCN2;OFCC1;WTIP;PKP4;ACTL8;JAK1;GFI1B;GLYR1;C5orf24

SDC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SDC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SDC1.

PECAM1; q7ci82_yerpe; MNDA; PYHIN1; PDCD6IP

Research Area

Related articles

Wang, HY; Jin, HN; et al. Cytoplasmic Domain Interactions of Syndecan-1 and Syndecan-4 with alpha 6 beta 4 Integrin Mediate Human Epidermal Growth Factor Receptor (HER1 and HER2)-dependent Motility and Survival. JOURNAL OF BIOLOGICAL CHEMISTRY 289:30318-30332(2014).
Gonzales, JC; Gordts, PLSM; et al. Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycans. JOURNAL OF CLINICAL INVESTIGATION 123:2742-2751(2013).
  • Q&As
  • Reviews

Q&As (7)

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In which tissues is SDC1 mainly expressed? 05/14/2022

SDC1 is predominantly expressed in epithelial tissues.

How is SDC1 linked to the ZEB1 transcription factor? 05/04/2022

The ZEB1 transcription factor acts on SDC1 and represses its expression.

How does SDC1 relate to the expression of the tight junction protein E-cadherin? 03/05/2022

SDC1 protein expression was positively correlated with E-cadherin protein expression and acted synergistically.

What are the effects of inhibiting SDC1 expression? 11/23/2021

Inhibition of SDC1 expression promotes tumor growth, invasion and metastasis.

What diseases is SDC1 involved in? 09/17/2021

SDC1 is involved in the study of diseases such as liver cancer, colon cancer and breast cancer.

Where is SDC1 located? 03/31/2021

SDC1 is localized to the cell membrane.

What biological processes is SDC1 involved in? 11/20/2020

SDC1 is involved in biological processes such as cell proliferation, differentiation, and adhesion.

Customer Reviews (3)

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Reviews
10/14/2023

    Each customer has a dedicated customer service to provide one-on-one, specialized service that solved the problem in my experiment.

    07/22/2023

      High quality product at a good price, a satisfactory shopping experience.

      07/13/2023

        The product brochure is very detailed and has comprehensive basic information about the SDC1 protein.

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