Recombinant Human SIGLEC8 Protein, MYC/DDK-tagged SIGLEC8-679H

Recombinant Human SIGLEC8 Protein, MYC/DDK-tagged


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Recombinant Human SIGLEC8 Protein, MYC/DDK-tagged

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Cat.No. : SIGLEC8-679H
Product Overview : Recombinant protein of human sialic acid binding Ig-like lectin 8 (SIGLEC8) was expressed in HEK293 cells with C-terminal MYC/DDK tag.
Description : Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490).
Source : HEK293
Species : Human
Molecular Mass : 53.9 kDa
Concentration : >50 ug/mL as determined by microplate BCA method.
Storage buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : SIGLEC8 sialic acid binding Ig-like lectin 8 [ Homo sapiens ]
Official Symbol : SIGLEC8
Synonyms : SIGLEC8; sialic acid binding Ig-like lectin 8; sialic acid-binding Ig-like lectin 8; MGC59785; SAF2; SIGLEC 8; SIGLEC8L; SAF-2; CDw329; sialoadhesin family member 2; SIGLEC-8;
Gene ID : 27181
mRNA Refseq : NM_014442
Protein Refseq : NP_055257
MIM : 605639
UniProt ID : Q9NYZ4

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