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Recombinant Human SIGLEC8 Protein, MYC/DDK-tagged

Cat.No. : SIGLEC8-679H
Product Overview : Recombinant protein of human sialic acid binding Ig-like lectin 8 (SIGLEC8) was expressed in HEK293 cells with C-terminal MYC/DDK tag.
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Description : Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490).
Source : HEK293
Species : Human
Tag : MYC/DDK
Molecular Mass : 53.9 kDa
Concentration : >50 ug/mL as determined by microplate BCA method.
Storage buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : SIGLEC8 sialic acid binding Ig-like lectin 8 [ Homo sapiens ]
Official Symbol : SIGLEC8
Synonyms : SIGLEC8; sialic acid binding Ig-like lectin 8; sialic acid-binding Ig-like lectin 8; MGC59785; SAF2; SIGLEC 8; SIGLEC8L; SAF-2; CDw329; sialoadhesin family member 2; SIGLEC-8;
Gene ID : 27181
mRNA Refseq : NM_014442
Protein Refseq : NP_055257
MIM : 605639
UniProt ID : Q9NYZ4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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