Recombinant Full Length Human SIGLEC8 Protein, C-Flag-tagged
Cat.No. : | SIGLEC8-1776HFL |
Product Overview : | Recombinant Full Length Human SIGLEC8 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 53.9 kDa |
AA Sequence : | MLLLLLLLPLLWGTKGMEGDRQYGD GYLLQVQELVTVQEGLCVHVPCSFS YPQDGWTDSDPVHGYWFRAG DRPYQDAPVATNNPDREVQAETQGR FQLLGDIWSNDCSLSIRDARKRDKG SYFFRLERGSMKWSYKSQLN YKTKQLSVFVTALTHRPDILILGTL ESGHPRNLTCSVPWACKQGTPPMIS WIGASVSSPGPTTARSSVLT LTPKPQDHGTSLTCQVTLPGTGVTT TSTVRLDVSYPPWNLTMTVFQGDAT ASTALGNGSSLSVLEGQSLR LVCAVNSNPPARLSWTRGSLTLCPS RSSNPGLLELPRVHVRDEGEFTCRA QNAQGSQHISLSLSLQNEGT GTSRPVSQVTLAAVGGAGATALAFL SFCIIFIIVRSCRKKSARPAAGVGD TGMEDAKAIRGSASQGPLTE SWKDGNPLKKPPPAVAPSSGEEGEL HYATLSFHKVKPQDPQGQEATDSEY SEIKIHKRETAETQACLRNH NPSSKEVRG TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, Transmembrane |
Gene Name : | SIGLEC8 sialic acid binding Ig like lectin 8 [ Homo sapiens (human) ] |
Official Symbol : | SIGLEC8 |
Synonyms : | SAF2; SIGLEC-8; SIGLEC8L |
Gene ID : | 27181 |
mRNA Refseq : | NM_014442.3 |
Protein Refseq : | NP_055257.2 |
MIM : | 605639 |
UniProt ID : | Q9NYZ4 |
Products Types
◆ Recombinant Protein | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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