Recombinant Human SIGLEC8 protein, His-tagged
Cat.No. : | SIGLEC8-772H |
Product Overview : | Recombinant Human SIGLEC8 (Met17-Ala363) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8. Siglec-8 was first identified by CD33 homology screening of ESTs from a cDNA library generated from a patient diagnosed with idiopathic hypereosinophilic syndrome and was originally termed SAF-2 (sialoadhesin family 2). At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Two splice variants of Siglec-8 exist. The initially characterized form contains 431 amino acid residues in total, subsequently, a longer form of Siglec-8, initially termed Siglec-8L. Both forms of Siglec-8 are found in eosinophils and contain a V-set domain with lectin activity and two C2-type Ig repeat domains in the extracellular region. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Met17 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 39.7 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Met17-Ala363 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | SIGLEC8 |
Official Symbol : | SIGLEC8 |
Synonyms : | SIGLEC8; sialic acid binding Ig-like lectin 8; sialic acid-binding Ig-like lectin 8; MGC59785; SAF2; SIGLEC 8; SIGLEC8L; SAF-2; CDw329; sialoadhesin family member 2; SIGLEC-8 |
Gene ID : | 27181 |
mRNA Refseq : | NM_014442 |
Protein Refseq : | NP_055257 |
MIM : | 605639 |
UniProt ID : | Q9NYZ4 |
Products Types
◆ Recombinant Protein | ||
SIGLEC8-679H | Recombinant Human SIGLEC8 Protein, MYC/DDK-tagged | +Inquiry |
SIGLEC8-6584H | Active Recombinant Human SIGLEC8 Protein, Fc-tagged | +Inquiry |
SIGLEC8-143H | Recombinant Human SIGLEC8 Protein, His (Fc)-Avi-tagged | +Inquiry |
SIGLEC8-197HB | Recombinant Human SIGLEC8 protein, His-Avi-tagged, Biotinylated | +Inquiry |
SIGLEC8-0693H | Recombinant Human SIGLEC8 protein, Fc-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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