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Active Recombinant Human ST2 Protein

Cat.No. : IL1RL1-1009H
Product Overview : Recombinant Human ST2 also known as interleukin-1receptor-like 1 antigen is produced by mammalian expression system and the target gene encoding Lys19- Phe328 is expressed with a 6His tag at the C-terminus. Predicted molecular weight: 60 kDa.
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Description : ST2 is an interleukin-1 family receptor expressed in the heart. ST2 protein has two isoforms: a soluble (sST2) and membrane- bound form. Patients with heart failure and elevated ST2 protein levels in the blood are at risk for heart failure progression.
Source : Human cells
Species : Human
Tag : His
Form : Lyophilized
Bio-activity : Anti-h ST2 10201: + Anti-h ST2 10202: + Anti-h ST2 10203: + Anti-h ST2 10204: + Anti-h ST2 10205: + Anti-h ST2 10206: + Anti-h ST2 10207: +
Molecular Mass : 60kDa
AA Sequence : KFSKQSWGLENEALIVRCPRQGKPS YTVDWYYSQTNKSIPTQERNRVFAS GQLLKFLPAAVADSG IYTCIVRSPTFNRTGYANVTIYKKQ SDCNVPDYLMYSTVSGSEKNSKIYC PTIDLYNWTAPLEWF KNCQALQGSRYRAHKSFLVIDNVMT EDAGDYTCKFIHNENGANYSVTATR SFTVKDEQGFSLFPV IGAPAQNEIKEVEIGKNANLTCSAC FGKGTQFLAAVLWQLNGTKITDFGE PRIQQEEGQNQSFSN GLACLDMVLRIADVKEEDLLLQYDC LALNLHGLRRHTVRLSRKNPSKECF VDHHHHHH
Purity : >90% by SDS-PAGE
Storage : -20centigrade
Concentration : 0.5 mg/ml when reconstituted with 100 µl of deionized wate
Storage Buffer : 20 mM Na-phosphate, pH 7.4, 150 mM NaCl
Reconstitution : Reconstitute lyophilized protein with 100 µl of deionized water
Gene Name : IL1RL1 interleukin 1 receptor-like 1 [ Homo sapiens ]
Official Symbol : IL1RL1
Synonyms : IL1RL1; interleukin 1 receptor-like 1; interleukin-1 receptor-like 1; DER4; FIT 1; homolog of mouse growth stimulation expressed; IL33R; ST2; ST2L; ST2V; T1; growth stimulation-expressed; interleukin 1 receptor-related protein; homolog of mouse growth stimulation-expressed; FIT-1; MGC32623;
Gene ID : 9173
mRNA Refseq : NM_003856
Protein Refseq : NP_003847
MIM : 601203
UniProt ID : Q01638

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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Are there any splice variants of IL1RL1? 02/20/2022

IL1RL1 has multiple splice variants that differ in signaling capabilities.

What is the role of IL1RL1 in allergic responses? 11/15/2021

IL1RL1 suppresses allergic responses by inhibiting mast cell activation.

Does IL1RL1 have a role in autoimmune diseases? 10/09/2021

IL1RL1 is implicated in rheumatoid arthritis.

How does IL1RL1 affect cytokine production? 11/21/2020

IL1RL1 increases the production of IL-4 and IL-13.

What is the subcellular localization of IL1RL1? 08/13/2020

IL1RL1 is primarily membrane-bound.

Does IL1RL1 influence T-cell differentiation? 02/29/2020

IL1RL1 promotes Th2 cell differentiation.

How does IL1RL1 interact with its ligands? 01/17/2020

IL1RL1 binds to IL-33 and IL-36 to initiate signaling.

Is IL1RL1 expression altered in any cancers? 05/09/2018

IL1RL1 expression is altered in lung and breast cancer.

What post-translational modifications occur on IL1RL1? 03/28/2017

IL1RL1 undergoes glycosylation and phosphorylation.

How is IL1RL1 expression regulated in asthmatic conditions? 08/23/2016

IL1RL1 expression is upregulated in asthmatic conditions.

Customer Reviews (3)

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Reviews
07/25/2019

    High specificity in ELISA.

    01/30/2017

      Suitable for flow cytometry.

      07/13/2016

        Effective in allergy models.

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