Recombinant Mouse Epha2 Protein, MYC/DDK-tagged

Cat.No. : Epha2-954M
Product Overview : Purified recombinant protein of full-length mouse Eph receptor A2 (Epha2), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
  • Specification
  • Gene Information
  • Related Products
Description : Broad expression in lung adult (RPKM 25.3), small intestine adult (RPKM 22.7) and 19 other tissues
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 109.3 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Epha2 Eph receptor A2 [ Mus musculus (house mouse) ]
Official Symbol : Epha2
Synonyms : Epha2; Eph receptor A2; Eck; Myk2; Sek2; Sek-2; AW545284; ephrin type-A receptor 2; epithelial cell kinase; tyrosine-protein kinase receptor ECK; tyrosine-protein kinase receptor MPK-5; tyrosine-protein kinase receptor SEK-2; EC 2.7.10.1
Gene ID : 13836
mRNA Refseq : NM_010139
Protein Refseq : NP_034269
UniProt ID : Q03145

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (6)

Ask a question
What are the treatment strategies for EPHA2? 08/01/2021

Therapeutic strategies for EPHA2 include inhibition of its expression, blocking its signal transduction pathway, and modulating its interaction with ligands. These strategies may involve the use of small molecule inhibitors, antibodies, or other types of therapeutics.

How does EPHA2 expression level relate to the occurrence and progression of the disease? 07/27/2021

The expression level of EPHA2 is associated with the occurrence and progression of a variety of diseases. For example, in tumors such as lung, breast, and colorectal cancer, EPHA2 expression levels may be elevated and correlated with the degree of malignancy and poor prognosis of the tumor.

How does EPHA2 expression level relate to tumor prognosis? 06/10/2021

In some tumors, EPHA2 expression levels are associated with poor prognosis in patients. For example, patients with lung cancer who express EPHA2 often have shorter survival. Therefore, the expression level of EPHA2 may be one of the indicators to predict tumor prognosis.

How can diseases be diagnosed by detecting EPHA2 expression levels? 05/21/2021

Some diseases can be diagnosed by measuring EPHA2 expression levels, such as immunohistochemistry, western blotting, and real-time PCR.

Could EPHA2 be used as a target for the treatment of certain diseases? 10/18/2020

Yes, EPHA2 can be used as a target for the treatment of certain diseases. For example, inhibition of EPHA2 expression can inhibit tumor growth and spread, so EPHA2 can serve as a potential therapeutic target. In addition, regulating the expression level of EPHA2 may also be helpful in the treatment of diseases such as the nervous system and cardiovascular system.

What is the role of EPHA2 in cancer metastasis? 08/22/2020

EPHA2 can promote cancer metastasis and affect the spread and spread of cancer by regulating processes such as invasion and migration of tumor cells. Therefore, inhibition of EPHA2 expression or blocking its signal transduction pathway may have a potential therapeutic effect on inhibiting cancer metastasis.

Customer Reviews (3)

Write a review
Reviews
12/21/2022

    The protein has low cytotoxicity.

    02/03/2022

      EPHA2 has good stability, and the test results of heat resistance, acid and alkali resistance and protease degradation resistance are good.

      03/31/2021

        Kinetic parameters such as enzymatic reaction rate and binding affinity were tested, and the protein performed well.

        Ask a Question for All Epha2 Products

        Required fields are marked with *

        My Review for All Epha2 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends